Sarcopenia clinical trials at University of California Health
2 research studies open to eligible people
Influence of Daily Grapes Intake on Sarcopenia in Postmenopausal Women
open to eligible females ages 60 years and up
Sarcopenia, characterized by loss of muscle mass and function, is a prevalent disorder in elderly individuals or individuals with chronic diseases. Given the above, there is an ongoing intensive search for novel therapies, including dietary ones, that can attenuate the loss of muscle mass and strength in the elderly. A proposed mechanism by which skeletal muscles might mediate their protective effect against sarcopenia is by secreting myokines as irisin. Phenolic compounds presents in grape have shown to be able to induce irisin secretion in muscle from rats supplemented with a grape pomace extract. The Ian of this study is to evaluate this mechanism in humans.
at UC Davis
Identifying Modifiable PAtient Centered Therapeutics (IMPACT) Frailty
open to eligible people ages 18 years and up
Frailty, the decline in physical and cognitive reserves leading to vulnerability to stressors is increasingly being recognized as a public health concern. Although multiple measures exist that can identify frail patients, very little is known about how or when to intervene. Sarcopenia, or the degree of muscle wasting, is closely correlated to frailty and patient outcomes. This is a prospective cohort study of critically ill patients to identify modifiable risk factors of sarcopenia, as potential targets to reduce frailty.
at UCLA
Our lead scientists for Sarcopenia research studies include Cecilia Canales, MD, MPH.
Last updated: