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Thyroid Gland Follicular Carcinoma clinical trials at UC Health
3 in progress, 2 open to new patients

  • Iodine I-131 With or Without Selumetinib in Treating Patients With Recurrent or Metastatic Thyroid Cancer

    open to eligible people ages 18 years and up

    This randomized phase II trial studies how well iodine I-131 works with or without selumetinib in treating patients with thyroid cancer that has returned or has spread from where it started to other places in the body. Many thyroid cancers absorb iodine. Due to this, doctors often give radioactive iodine (iodine I-131) alone to treat thyroid cancer as part of standard practice. It is thought that the more thyroid tumors are able to absorb radioactive iodine, the more likely it is that the radioactive iodine will cause those tumors to shrink. Selumetinib may help radioactive iodine work better in patients whose tumors still absorb radioactive iodine. It is not yet known whether iodine I-131 is more effective with or without selumetinib in treating thyroid cancer.

    at UCSD

  • Lenvatinib and Pembrolizumab in DTC

    open to eligible people ages 18 years and up

    This phase II trial studies how well pembrolizumab and lenvatinib work in treating patients with differentiated thyroid cancer that has spread to other places in the body or has come back and cannot be removed by surgery. Monoclonal antibodies, such as pembrolizumab, may stimulate the immune system to attack the cancer, and kinase inhibitors, such as lenvatinib, may interfere with the ability of tumor cells to grow and spread.

    at UCSD UCLA

  • Cediranib Maleate With or Without Lenalidomide in Treating Patients With Thyroid Cancer

    Sorry, in progress, not accepting new patients

    This partially randomized phase I/II trial studies the side effects and best dose of cediranib maleate when given together with or without lenalidomide and to see how well they work in treating patients with thyroid cancer. Cediranib maleate may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Lenalidomide may stop the growth of thyroid cancer by blocking blood flow to the tumor. It is not yet known whether cediranib maleate is more effective when given together with lenalidomide in treating thyroid cancer.

    at UC Davis

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