Summary

for people ages 5 years and up (full criteria)
healthy people welcome
at UCSD
study started
estimated completion:
Matthew A Allison (ucsd)

Description

Summary

Avocados are an excellent source of fiber, potassium, magnesium, and poly- and mono-unsaturated fats. They can be a nutrient dense component of healthful dietary patterns and have the potential to improve the cardiovascular disease (CVD) risk profiles of families in the United States (US). The proposed research plan will focus on the contribution of avocado intake to the reduction in CVD risk of US families, by examining the effects of avocado intake on the overall nutritional status of families. Of particular interest is establishing these effects in ethnic populations such as Hispanics/Latinos. On average, Hispanic/Latinos are at increased risk for metabolic diseases that predispose to CVD. This 6-month cluster randomized trial in Hispanic/Latino Americans aims to accurately determine the impact of avocados on the overall dietary pattern of their families. Future research will extend the results of the current trial to a larger sample of ethnically diverse families in order to evaluate whether sustained changes occur in nutritional, cardiovascular and metabolic health status.

Details

Specific Aim 1: To determine how avocados are incorporated into the family's dietary pattern and impact selected measures of nutritional status:

  1. To determine if avocado intake substitutes for, or adds to, other sources of calories in the family diet.
  2. To determine if avocado intake helps reduce between-meal snacking of family members.
  3. To determine if avocados help families meet US Dietary Guidelines for recommended intake of: poly- and monounsaturated fats; vegetables; fiber; selected nutrients (vitamins C, D and E, Folate, Calcium, Magnesium, potassium, iron); lutein and other carotenoids.

Specific aim 2: To determine if increased avocado intake affects cardio-metabolic risk factors to include lipids, glucose, insulin, and HbA1c.

Keywords

Cardiovascular Disease Avocado Cardiovascular Diseases High-intake avocados Low-intake avocados Diet tips Avocado consumption advice

Eligibility

You can join if…

Open to people ages 5 years and up

  1. Be part of a family that consists of at least 3 individuals, but no more than 8, who reside in the same home
  2. Self-identify as Latino or Hispanic
  3. Be older than 5 years of age

You CAN'T join if...

  1. Families with members who have clinically severe chronic diseases requiring specific diets (e.g. stage IV congestive heart failure, chronic kidney disease requiring dialysis)
  2. Those allergic to avocados
  3. Those with LATEX allergy
  4. Families who are already high consumers of avocados (i.e. more than 1 avocado per adult and more than ½ avocado per child per day);
  5. Those who are unwilling to eat avocados.
  6. Family members with nursing or pregnant females or females planning to become pregnant
  7. Family members under the age of 5 years will not be counted toward the number of family members who will be expected to participate in the intervention (i.e., adhere to healthy diet tips or consume avocados)
  8. Families intending to move, or which include family members intending to move, within the next 6 months

Location

  • South Bay Latino Research Center accepting new patients
    Chula Vista California 91910 United States

Lead Scientist

  • Matthew A Allison (ucsd)
    Matthew A. Allison, MD, MPH is Professor and Chief, Division of Preventive Medicine in the Department of Family Medicine and Public Health at the University of California San Diego. Dr. Allison earned his undergraduate degree in Biochemistry from the California Polytechnic State University and a Doctorate in Medicine from the Uniformed Services University.

Details

Status
accepting new patients
Start Date
Completion Date
(estimated)
Sponsor
University of California, San Diego
ID
NCT02903433
Study Type
Interventional
Last Updated