Summary

for people ages 20-75 (full criteria)
healthy people welcome
at UC Davis
study started
estimated completion:

Description

Summary

To evaluate if a commonly used medical bone scan, called positron emission tomography/computed tomography (PET/CT) with sodium fluoride can measure bone blood flow to the hip.

Official Title

A Feasibility Study to Determine PET/CT Imaging of Blood Flow to the Bone

Details

The purpose of this research is to validate technique on a commonly used medical bone scan, called positron emission tomography/computed tomography (PET/CT) along with sodium fluoride as the tracer for determining blood flow to the bone. Up to 12 subjects will have PET/CT scans so that we can determine the repeatability and reliability of the images prior to using PET/CT for this use on subjects in the Phase 1b part of Dr. Nancy Lane's clinical research study entitled "A Phase 1, Randomized, Double-Blind, Placebo-Controlled Single and Multiple Ascending Dose Study of the Safety and Tolerability of Intravenous LLP2A-Alendronate in Adult Men and Women with Osteopenia Secondary to Glucocorticoids" (IRB Protocol #866350).

Keywords

Normal Subjects Fluorides Sodium Fluoride Listerine PET/CT Scan

Eligibility

You can join if…

Open to people ages 20-75

Subjects must meet all of the following criteria to be included in the study.

  1. 20 - 75 years old
  2. Must be ambulatory and able to attend all appointments
  3. Women must agree to use one of the following methods of birth control for the duration of the clinical trial:

systemic hormonal contraceptive (oral, injected, transdermal), intrauterine device,double barrier (e.g., cervical cap or diaphragm with condom or spermicide). Men with female partners must agree to use double barrier contraception, unless their partner is using systemic hormonal contraceptives or has an intrauterine device

  1. Subject undergoing PET/CT scans must have the ability to lay motionless for up to 30 minutes.

You CAN'T join if...

  1. Subjects undergoing PET/CT scans must not be breast-feeding.
  2. History of hypersensitivity to fluoride

Location

  • UC Davis accepting new patients
    Sacramento California 95817 United States

Details

Status
accepting new patients
Start Date
Completion Date
(estimated)
Sponsor
University of California, Davis
ID
NCT03557450
Study Type
Interventional
Last Updated
June 25, 2018