Summary

for females ages 16 years and up (full criteria)
healthy people welcome
study started
estimated completion
Dvora Joseph Davey(ucla)

Description

Summary

The overarching goal of this proposal is to evaluate the feasibility and acceptability of integrating PrEP into antenatal and postnatal care, to describe the cascade in women initiating PrEP in this setting, and to evaluate the reasons for attrition along the PrEP cascade in a cohort of pregnant and breastfeeding women. The specific aims are to: (1) Evaluate the feasibility and acceptability of integrating PrEP into antenatal and postnatal/well-baby services; (2) Describe the PrEP cascade of initiation, retention, and adherence in a cohort of 220 HIV-uninfected pregnant and breastfeeding women, (3) Evaluate attrition and associated factors across the PrEP cascade.

Official Title

Evaluation of Pre-exposure Prophylaxis Cascade in Pregnant and Breastfeeding Women in Cape Town, South Africa (Formative Study)

Keywords

Hiv pre-exposure prophylaxis PrEP pregnancy prevention of mother to child transmission PMTCT TDF-FTC Counselling on PrEP in antenatal and postnatal care

Eligibility

You can join if…

Open to females ages 16 years and up

  1. Documented HIV-negative according to two fingerpick rapid tests (per routine antenatal care protocol in this setting), confirmed with a 4th generation antigen HIV test at study enrollment
  2. No previous exposure triple-drug antiretroviral therapy
  3. Age 18 years or older
  4. Lives within 20 kilometers of a clinic
  5. Without psychiatric or medical contraindications to PrEP use
  6. Able to provide informed consent for research

You CAN'T join if...

Failure to meet any of the inclusion criteria

Lead Scientist

Details

Status
not yet accepting patients
Start Date
Completion Date
(estimated)
Sponsor
University of California, Los Angeles
ID
NCT03826199
Phase
Phase 4
Study Type
Interventional
Last Updated