EXPLORER PET/CT in Healthy Volunteers

Summary

for people ages 18 years and up (full criteria)
healthy people welcome
at UC Davis
study started
estimated completion
Lorenzo Nardo, MD(ucdavis)

Description

Summary

The objective of this pilot study is to collect preliminary data using total body scans on a new, first of its kind, FDA 510k-cleared positron emission tomography/computed tomography (PET/CT) scanner, called EXPLORER.

Official Title

EXPLORER PET/CT: A Pilot Evaluation in Healthy Volunteers

Keywords

Healthy EXPLORER PET/CT delayed imaging acquisition low FDG dose imaging

Eligibility

You can join if…

Open to people ages 18 years and up

  • Men and women, 18 years of age or older
  • Willing and able to fast for at least 6 hours before and for the duration of the scan
  • Willing and able to lay motionless in a supine position for 60 and 20 minutes at separate timepoints.
  • Willing and able to give informed consent

You CAN'T join if...

  • No Primary Care Physician
  • Body weight >240 kg
  • Allergy to iodine contrast (only for subjects enrolled in Arm 3)
  • Creatinine levels > 1.5 mg/dL or estimated glomerular filtration rate (eGFR) < 60 ml/minute (only for subjects enrolled in Arm 3)
  • Recent (1 month) contrast enhanced CT
  • Any known concomitant acute infection (including upper respiratory infection, genitourinary infections, etc.
  • History of metastatic or newly (last 5 years) diagnosed locally invasive cancer.
  • Chemotherapy in the last 5 years
  • Radiation therapy in the last 3 years
  • Major surgery within the last 6 months.
  • Pregnancy or breast-feeding
  • Diabetes
  • Fasting blood glucose level > 160 mg/dL before administration of FDG
  • Prisoners
  • The standard MRI contraindications apply, including but not limited to:

Having a pacemaker or other implanted electronic device. Metal foreign bodies, aneurysm clips, heart valve prosthesis, vascular stents, cochlear implants, embolization coils, gunshot wounds with retained bullet fragments, penile implant, IUCD.

Claustrophobia

Location

  • University of California, Davis accepting new patients
    Sacramento California 95817 United States

Lead Scientist

  • Lorenzo Nardo, MD (ucdavis)
    Assistant Professor, Radiology. Authored (or co-authored) 73 research publications.

Details

Status
accepting new patients
Start Date
Completion Date
(estimated)
Sponsor
University of California, Davis
ID
NCT04110743
Phase
Phase 1
Study Type
Interventional
Last Updated