Summary

Eligibility
for people ages 18 years and up (full criteria)
Healthy Volunteers
healthy people welcome
Location
at UC Davis
Dates
study started
estimated completion
Principal Investigator
Neal Fleming, MD (ucdavis)

Description

Summary

This investigator initiated, prospective, observational, single-center study is designed to assess whether dynamic monitors of cardiac function such as stroke volume variation (SVV) that have been shown to predict volume responsiveness differ in clinical utility between patients with and without diastolic dysfunction.

Official Title

Evaluation of Dynamic Monitors for the Prediction of Volume Responsiveness in Patients With and Without Diastolic Dysfunction

Details

This investigator initiated, prospective, observational, single-center study is designed to assess whether dynamic monitors of cardiac function, such as stroke volume variation (SVV), that have been shown to predict volume responsiveness differ in clinical utility between patients with and without diastolic dysfunction.

Specific Aims:

  • Determine the threshold for the predictive response of SVV with respect to increasing cardiac output for patients with and without diastolic dysfunction.
  • Compare the trans thoracic ultrasound assessment of left ventricular diastolic function before and after the induction of general anesthesia.

Keywords

Stroke Volume Variation Diastolic Dysfunction Trans thoracic Ultrasound Examination Intravenous fluid administration

Eligibility

You can join if…

Open to people ages 18 years and up

  • Patients Undergoing Elective surgical procedures where invasive arterial line pressure monitoring is a planned part of the intraoperative management
  • Age greater than or equal to 18
  • Procedures requiring general anesthesia and mechanical ventilation

You CAN'T join if...

  • Adults unable to provide consent
  • Atrial Fibrillation or other significant active arrhythmia
  • Emergency Procedures
  • Hemodynamic instability requiring vasopressor and/or inotropic infusions
  • Presence of an intra-aortic balloon pump
  • Open thoracic procedures
  • Extremes of BMI less than 20 or greater than 40
  • Pregnancy
  • Prisoners
  • Patient Refusal

Location

  • UC Davis Health System accepting new patients
    Sacramento California 95817 United States

Lead Scientist at UC Health

  • Neal Fleming, MD (ucdavis)
    Professor, Anesthesiology and Pain Medicine. Authored (or co-authored) 56 research publications.

Details

Status
accepting new patients
Start Date
Completion Date
(estimated)
Sponsor
University of California, Davis
ID
NCT04177225
Study Type
Observational
Last Updated