Summary

Eligibility
for people ages 18-100 (full criteria)
Healthy Volunteers
healthy people welcome
Location
at UCLA
Dates
study started
completion around
Principal Investigator
by V. Raman Muthusamy, MD (ucla)

Description

Summary

A prospective outcomes study in patients with and esophageal cancer (EAC) and Barrett's esophagus (BE) associated neoplasia being evaluated for endoscopic eradication therapy (EET).

Official Title

A Multicenter Prospective Study Evaluating Outcomes of Endoscopic Eradication Therapy in Patients With Barrett's Esophagus Associated Neoplasia: The TREAT-BE (Treatment With Resection and Endoscopic Ablation Techniques for Barrett's Esophagus) Consortium

Details

Patients will be enrolled in this study at the participating centers when evaluated in gastro-intestinal (GI) clinics and endoscopy suites. Initial evaluation of patients will include collection of data on demographics, assessment of risk factors such as smoking, metabolic syndrome, family history and detailed medication history, and past surgical history. All patients will be complete questionnaires regarding Gastroesophageal Reflux Disease (GERD) symptoms, GERD related quality of life (QOL) and overall health related QOL. Details of all previous endoscopic and surgical evaluation along with histopathology data will be documented. Patients undergoing endoscopic evaluation at the participating centers will have their endoscopic and histopathology results documented. This will include data collection regarding use of advanced imaging techniques, details regarding tissue acquisition, EET and adverse events. Patients undergoing esophagectomy will have surgical details documented along with complications related to surgery. Similarly, details regarding chemoradiation treatments will be documented .

Keywords

Barrett's Esophagus, Esophageal Cancer, Barrett Esophagus, Endoscopic eradication therapies (EET), Esophagectomy, Chemotherapy, Radiation

Eligibility

You can join if…

Open to people ages 18-100

You CAN'T join if...

Locations

  • UCLA Medical Center accepting new patients
    Los Angeles California 90095 United States
  • Washington University accepting new patients
    Saint Louis Missouri 63130 United States
  • Northwestern Memorial Hospital accepting new patients
    Chicago Illinois 60611 United States
  • Moffitt Cancer Center accepting new patients
    Tampa Florida 33612 United States

Lead Scientist at University of California Health

  • V. Raman Muthusamy, MD (ucla)
    Venkataraman Raman Muthusamy, M.D., holds the Leon J. Tiber, M.D. and David S. Alpert, M.D. Chair in Medicine.

Details

Status
accepting new patients
Start Date
Completion Date
(estimated)
Sponsor
University of Colorado, Denver
ID
NCT02634645
Study Type
Observational
Participants
Expecting 5000 study participants
Last Updated