Clinical trials open to people over 65
(1244 trials open to new patients)
- Acute Kidney Injury (2 open to new patients)
- Acute Lung Injury (1 open to new patients)
- Acute Lymphoblastic Leukemia (6 open to new patients)
- Acute Myeloid Leukemia (7 open to new patients)
- Acute Respiratory Distress Syndrome (1 open to new patients)
- Adenocarcinoma of the Rectum (1 open to new patients)
- Adenovirus (2 open to new patients)
- Adiposity (1 open to new patients)
- Adrenocortical Carcinoma (1 open to new patients)
- Aging Problems (1 open to new patients)
- Agitation (1 open to new patients)
- Alcohol Use (3 open to new patients)
- Allogeneic Hematopoietic Cell Transplantation (2 open to new patients)
- Alpha-1 Antitrypsin Deficiency (4 open to new patients)
- Alzheimer's Disease (18 open to new patients)
- Amnestic Mild Cognitive Disorder (1 open to new patients)
- Amputation (4 open to new patients)
- Amyotropic Lateral Sclerosis (ALS) (3 open to new patients)
- Anarthria (1 open to new patients)
- Anemia (6 open to new patients)
- Anesthesia (1 open to new patients)
- Aneurysm (3 open to new patients)
- Anti-Synthetase Syndrome (1 open to new patients)
- Anxiety (6 open to new patients)
- Anxiety in Pregnancy (1 open to new patients)
- Aortic Disease (1 open to new patients)
- Aortic Stenosis (1 open to new patients)
- Apical Abscess (1 open to new patients)
- Arteriovenous Fistula (1 open to new patients)
- Arthritis (5 open to new patients)
- Asplenia (1 open to new patients)
- Asthma (8 open to new patients)
- Astrocytoma (8 open to new patients)
- Atherosclerosis (2 open to new patients)
- Atopic Dermatitis (Eczema) (2 open to new patients)
- Atrial Fibrillation (2 open to new patients)
- Attempted Suicide (1 open to new patients)
- ATTR (1 open to new patients)
- ATTR-CM (1 open to new patients)
- ATTR-Mixed (1 open to new patients)
- ATTRv-PN (1 open to new patients)
- Atypical Parkinsonism (1 open to new patients)
- Auditory Perceptual Impairment (1 open to new patients)
- Autoimmune Disease (1 open to new patients)
- Avascular Necrosis (1 open to new patients)
- B-Cell Acute Lymphoblastic Leukemia (2 open to new patients)
- Back Pain (7 open to new patients)
- Bariatric Surgery (2 open to new patients)
- Barrett's Esophagus (2 open to new patients)
- Basal Cell Carcinoma (1 open to new patients)
- Biliary Tract Cancer (1 open to new patients)
- Bipolar Disorder (1 open to new patients)
- Bladder Cancer (2 open to new patients)
- Bladder Diseases (1 open to new patients)
- Bladder, Neurogenic (1 open to new patients)
- Blood Loss (1 open to new patients)
- Bone and Joint Infection (1 open to new patients)
- Bone Infection (1 open to new patients)
- Bone Marrow Transplant (4 open to new patients)
- Brain Cancer (3 open to new patients)
- Brain-Derived Neurotrophic Factor (1 open to new patients)
- Brain Fog (1 open to new patients)
- Brain Injury (7 open to new patients)
- Brain Stem Infarctions (2 open to new patients)
- Brain Tumor (4 open to new patients)
- Breast Cancer (15 open to new patients)
- Breast Screening (1 open to new patients)
- Bronchiolitis Obliterans (1 open to new patients)
- Burn Injury (1 open to new patients)
- Cancer Awareness and Prevention Education (1 open to new patients)
- Cancer, General (7 open to new patients)
- Cannabidiol (2 open to new patients)
- Cannabis (4 open to new patients)
- Carcinoma (11 open to new patients)
- Cardiometabolic Syndrome (1 open to new patients)
- Cardiomyopathy (6 open to new patients)
- Cardiopulmonary Bypass (1 open to new patients)
- Cardiovascular Disease (4 open to new patients)
- Cataracts (1 open to new patients)
- CD19 Positive (1 open to new patients)
- CD20 Positive (1 open to new patients)
- CDD (1 open to new patients)
- CDKL5 Deficiency Disorder (1 open to new patients)
- Cervical Disc Degenerative Disorder (1 open to new patients)
- Child Development (1 open to new patients)
- Cholangiocarcinoma (1 open to new patients)
- Chondrosarcoma (1 open to new patients)
- Chronic Fatigue (1 open to new patients)
- Chronic Kidney Disease (6 open to new patients)
- Chronic Limb-Threatening Ischemia (1 open to new patients)
- Chronic Lymphocytic Leukemia (3 open to new patients)
- Chronic Myeloid Leukemia (1 open to new patients)
- Chronic Myelomonocytic Leukemia (1 open to new patients)
- Chronic Obstructive Pulmonary Disease (5 open to new patients)
- Chronic Rhinosinusitis (2 open to new patients)
- Cirrhosis (7 open to new patients)
- Cocaine Use (1 open to new patients)
- Cognition (1 open to new patients)
- Cognitive Behavioral Therapy (2 open to new patients)
- Cognitive Change (1 open to new patients)
- Cognitive Decline (3 open to new patients)
- Cognitive Dysfunction (1 open to new patients)
- Cognitive Impairment (4 open to new patients)
- Colon Cancer (2 open to new patients)
- Colon Polyps (1 open to new patients)
- Colorectal Cancer (9 open to new patients)
- Colorectal Tumor (5 open to new patients)
- Complex Regional Pain Syndrome (3 open to new patients)
- Concentration Ability Impaired (1 open to new patients)
- Concussion (1 open to new patients)
- Connective Tissue Diseases (1 open to new patients)
- Constipation (1 open to new patients)
- Contingency Management (1 open to new patients)
- Continuous Glucose Monitoring (1 open to new patients)
- Copy Number Variation (2 open to new patients)
- Coronary Artery Bypass (1 open to new patients)
- Coronary Artery Disease (4 open to new patients)
- COVID-19 (4 open to new patients)
- CPAP (1 open to new patients)
- Critical Limb Ischemia (1 open to new patients)
- Crohn's Disease (2 open to new patients)
- Cystic Fibrosis (2 open to new patients)
- Cytomegalovirus (1 open to new patients)
- Deep Brain Stimulation (7 open to new patients)
- Degenerative Joint Disease of Knee (1 open to new patients)
- Delirium (1 open to new patients)
- Dementia (9 open to new patients)
- Depression (24 open to new patients)
- Dermatitis (1 open to new patients)
- Dermatologic Diseases (1 open to new patients)
- Dermatomyositis (1 open to new patients)
- Diabete Mellitus (1 open to new patients)
- Diabetes (16 open to new patients)
- Diabetes Type 1 (2 open to new patients)
- Diabetes Type 2 (7 open to new patients)
- Diabetic Ulcer (2 open to new patients)
- Dialysis (3 open to new patients)
- Diffuse Large B-Cell Lymphoma (6 open to new patients)
- Diffuse Scleroderma (2 open to new patients)
- Discrimination, Racial (1 open to new patients)
- Dislocated Shoulder (1 open to new patients)
- Dislocations (1 open to new patients)
- Dysarthria (1 open to new patients)
- Dysplasia (3 open to new patients)
- Electronic Cigarettes (1 open to new patients)
- Emotional Memory (1 open to new patients)
- Emphysema (1 open to new patients)
- End of Life (2 open to new patients)
- End Stage Renal Disease (2 open to new patients)
- Endometrial Cancer (1 open to new patients)
- Eosinophilic Esophagitis (1 open to new patients)
- Epilepsy (3 open to new patients)
- Epistaxis (1 open to new patients)
- Epstein Barr Virus (1 open to new patients)
- Erectile Dysfunction (1 open to new patients)
- Erythropoietic Protoporphyria (1 open to new patients)
- Esophageal Cancer (2 open to new patients)
- Ewing Sarcoma (1 open to new patients)
- Executive Dysfunction (1 open to new patients)
- Fabry Disease (2 open to new patients)
- Facio-Scapulo-Humeral Dystrophy (1 open to new patients)
- Facioscapulohumeral Muscular Dystrophy (1 open to new patients)
- Fatigue (2 open to new patients)
- Fear (1 open to new patients)
- Fibromyalgia (1 open to new patients)
- Fibrosis (9 open to new patients)
- Fistula (1 open to new patients)
- FKRP (1 open to new patients)
- FKRP Mutation (1 open to new patients)
- FMD (1 open to new patients)
- FMD2 (1 open to new patients)
- Focal Segmental Glomerulosclerosis (2 open to new patients)
- Frontotemporal Dementia (2 open to new patients)
- FSH (1 open to new patients)
- Fukutin Related Protein (1 open to new patients)
- GAD (1 open to new patients)
- Gastroesophageal Junction Cancer (1 open to new patients)
- Gastroparesis (1 open to new patients)
- GERD (1 open to new patients)
- Glanzmann Thrombasthenia (1 open to new patients)
- Glioblastoma (8 open to new patients)
- Glioma (10 open to new patients)
- Gliosarcoma (1 open to new patients)
- Glomerulonephritis (3 open to new patients)
- Glucose Intolerance (1 open to new patients)
- Gulf War Syndrome (4 open to new patients)
- hATTR (1 open to new patients)
- Head and Neck Cancer (4 open to new patients)
- Head and Neck Squamous Cell Carcinoma (4 open to new patients)
- Headache (6 open to new patients)
- Health Care Utilization (1 open to new patients)
- Health Disparities (1 open to new patients)
- Health Knowledge, Attitudes, Practice (1 open to new patients)
- Heart Conditions (3 open to new patients)
- Heart Disease (4 open to new patients)
- Heart Failure (3 open to new patients)
- Hematologic Malignancy (3 open to new patients)
- Hematologic Neoplasms (3 open to new patients)
- Hematopoietic Cell Transplantation (3 open to new patients)
- Hemolytic-Uremic Syndrome (1 open to new patients)
- Hemophilia (1 open to new patients)
- Hemorrhagic Stroke (2 open to new patients)
- Hepatic Impairment (1 open to new patients)
- Hepatic Veno-Occlusive Disease (1 open to new patients)
- Hepatitis (2 open to new patients)
- Hepatitis A (2 open to new patients)
- Hepatitis B (3 open to new patients)
- Hepatitis C (1 open to new patients)
- Hepatocellular Cancer (5 open to new patients)
- HER2 (2 open to new patients)
- HHT (1 open to new patients)
- High Blood Pressure (9 open to new patients)
- HIV/AIDS (9 open to new patients)
- Hoarding Disorder (1 open to new patients)
- Huntington's Disease (1 open to new patients)
- Hypersensitivity Pneumonitis (1 open to new patients)
- Hypothyroidism (1 open to new patients)
- Idiopathic Gastroparesis (1 open to new patients)
- Idiopathic Pulmonary Fibrosis (2 open to new patients)
- IgA Nephropathy (1 open to new patients)
- Immunodeficiency (5 open to new patients)
- Inflammation (3 open to new patients)
- Inflammatory Bowel Disease (8 open to new patients)
- Insomnia (3 open to new patients)
- Insulin Resistance (1 open to new patients)
- Intellectual Disability (1 open to new patients)
- Interstitial Cystitis (1 open to new patients)
- Interstitial Lung Disease (3 open to new patients)
- Intracranial Hemorrhage (2 open to new patients)
- Irritable Bowel Syndrome (1 open to new patients)
- Ischemic Necrosis (1 open to new patients)
- Ischemic Stroke (1 open to new patients)
- Joint Infection (1 open to new patients)
- Joint Pain (1 open to new patients)
- Ketamine (1 open to new patients)
- Ketogenic Diet (1 open to new patients)
- Kidney Cancer (2 open to new patients)
- Kidney Disease (11 open to new patients)
- Kidney Transplant (6 open to new patients)
- Knee Pain (1 open to new patients)
- Knee Replacement (1 open to new patients)
- Lactation Disorder With Baby Delivered (1 open to new patients)
- Laryngopharyngeal Reflux (1 open to new patients)
- Lateral Epicondylitis, Unspecified Elbow (1 open to new patients)
- Left Ventricular Dysfunction (1 open to new patients)
- Left Ventricular Ejection Fraction (1 open to new patients)
- Left Ventricular Hypertrophy (1 open to new patients)
- Leukemia (12 open to new patients)
- Lewy Body Dementia (1 open to new patients)
- LGMD2 (1 open to new patients)
- LGMD2I (1 open to new patients)
- Limb-Girdle Muscular Dystrophy (1 open to new patients)
- Liquid Biopsy (1 open to new patients)
- Liver Cancer (5 open to new patients)
- Liver Disease (10 open to new patients)
- Liver Transplant (2 open to new patients)
- Locked in Syndrome (2 open to new patients)
- Loneliness (1 open to new patients)
- Long-Term Memory Decline (1 open to new patients)
- Lower Back Pain (6 open to new patients)
- Lung Cancer (13 open to new patients)
- Lung Transplant (3 open to new patients)
- Lung Tumor (6 open to new patients)
- Lupus (12 open to new patients)
- Lymphoid Malignancies (1 open to new patients)
- Lymphoma (11 open to new patients)
- Macular Degeneration (5 open to new patients)
- Malignant Neoplasm (3 open to new patients)
- Mantle Cell Lymphoma (1 open to new patients)
- MECP2 Duplication Syndrome (1 open to new patients)
- Meditation (4 open to new patients)
- Membranous Nephropathy (2 open to new patients)
- Memory Deficits (1 open to new patients)
- Memory, Delayed (2 open to new patients)
- Memory Disorders (2 open to new patients)
- Memory Disorder, Spatial (1 open to new patients)
- Memory Impairment (1 open to new patients)
- Memory Loss (1 open to new patients)
- Meniere's Disease (1 open to new patients)
- Meningioma (1 open to new patients)
- Menopause (1 open to new patients)
- Mental Disorder (1 open to new patients)
- Mental Health (2 open to new patients)
- Metabolic Acidosis (1 open to new patients)
- Metabolic Disease (1 open to new patients)
- Metabolic Syndrome (2 open to new patients)
- Metastatic Castration-Resistant Prostate Cancer (2 open to new patients)
- Methamphetamines (1 open to new patients)
- Microbiome (1 open to new patients)
- Microsatellite Instability (1 open to new patients)
- Migraine (2 open to new patients)
- Mild Cognitive Impairment (13 open to new patients)
- Mindfulness (1 open to new patients)
- Minimal Change Disease (1 open to new patients)
- Mitochondrial Energetics (1 open to new patients)
- Mitral Valve Insufficiency (1 open to new patients)
- Mouth Diseases (1 open to new patients)
- Multiple Myeloma (1 open to new patients)
- Multiple Sclerosis (8 open to new patients)
- Multiple System Atrophy (2 open to new patients)
- Muscle Pain (1 open to new patients)
- Muscular Atrophy (1 open to new patients)
- Muscular Dystrophies (4 open to new patients)
- Myasthenia Gravis (2 open to new patients)
- Myelodysplastic Syndrome (3 open to new patients)
- Myelofibrosis (1 open to new patients)
- Myocarditis (1 open to new patients)
- Myopathy (1 open to new patients)
- Myotonia (1 open to new patients)
- Myotonic Disorders (1 open to new patients)
- Myotonic Dystrophy (2 open to new patients)
- Nasal Polyps (1 open to new patients)
- Neck Pain (1 open to new patients)
- Neoplasms (14 open to new patients)
- Nephrotic Syndrome (1 open to new patients)
- Nerve Injury (2 open to new patients)
- Nerve Root Avulsion (2 open to new patients)
- Neuroblastoma (1 open to new patients)
- Neurocognitive Disorder (3 open to new patients)
- Neurocognitive Dysfunction (1 open to new patients)
- Neurodegenerative Disease (1 open to new patients)
- Neuroendocrine Tumor (1 open to new patients)
- Neurogenic Bladder (1 open to new patients)
- Neuroimaging (6 open to new patients)
- Neuroinflammatory Disease (1 open to new patients)
- Neuroinflammatory Response (1 open to new patients)
- Neurologic Disorder (1 open to new patients)
- Neuropathic Pain (1 open to new patients)
- Nicotine (2 open to new patients)
- Non-Hodgkin Lymphoma (6 open to new patients)
- Non-Small Cell Lung Cancer (7 open to new patients)
- Nonalcoholic Fatty Liver Disease (4 open to new patients)
- Nonalcoholic Steatohepatitis (2 open to new patients)
- Nosebleed (1 open to new patients)
- Nutrition Disorder, Infant (1 open to new patients)
- Obesity (10 open to new patients)
- Obsessive-Compulsive Disorder (2 open to new patients)
- Ocular Melanoma (2 open to new patients)
- Opioid Use (3 open to new patients)
- Organ Preservation (1 open to new patients)
- Osteoarthritis (3 open to new patients)
- Osteomyelitis (1 open to new patients)
- Osteonecrosis (1 open to new patients)
- Ovarian Cancer (3 open to new patients)
- Ovarian Epithelial Carcinoma (1 open to new patients)
- Overlap Syndrome (1 open to new patients)
- Pain (15 open to new patients)
- Pancreatic Cancer (3 open to new patients)
- Pancreatic Cyst (3 open to new patients)
- Pancreatic Ductal Adenocarcinoma (3 open to new patients)
- Pancreatic Neoplasms (3 open to new patients)
- Panic Disorder (1 open to new patients)
- Parkinson's Disease (7 open to new patients)
- Patent Foramen Ovale (1 open to new patients)
- Pathologic Processes (1 open to new patients)
- Patient Satisfaction (1 open to new patients)
- Perceived Stress (1 open to new patients)
- Perfusion (1 open to new patients)
- Periodontitis (1 open to new patients)
- Peripheral Artery Disease (6 open to new patients)
- Peritoneal Cancer (1 open to new patients)
- Peritoneal Carcinomatosis (1 open to new patients)
- Persistent Disease (1 open to new patients)
- Phantom Limb (1 open to new patients)
- Pheochromocytoma (1 open to new patients)
- Phobia (1 open to new patients)
- Physical Endurance (1 open to new patients)
- Physical Function (1 open to new patients)
- Physical Illness (1 open to new patients)
- Physical Inactivity (1 open to new patients)
- Physical Injury (1 open to new patients)
- PIK3CA-Related Overgrowth Spectrum (1 open to new patients)
- Platelet Aggregation, Spontaneous (1 open to new patients)
- Pneumonia (1 open to new patients)
- Pompe Disease (1 open to new patients)
- Post Operative Surgical Site Infection (1 open to new patients)
- Post Radiation Plexopathy (1 open to new patients)
- Post-Stroke Pain (2 open to new patients)
- Post-Traumatic Headache (1 open to new patients)
- Post-traumatic Stress (1 open to new patients)
- Post-Traumatic Stress Disorder (9 open to new patients)
- Postherpetic Neuralgia (2 open to new patients)
- Postoperative Nausea and Vomiting (1 open to new patients)
- Postoperative Outcome (1 open to new patients)
- Postoperative Pain (3 open to new patients)
- Postpartum Depression (1 open to new patients)
- Prediabetes (2 open to new patients)
- Pregnancy (1 open to new patients)
- Primary Biliary Cholangitis (3 open to new patients)
- Primary Immunodeficiency Diseases (4 open to new patients)
- Primary Progressive Aphasia (2 open to new patients)
- Primary Sclerosing Cholangitis (1 open to new patients)
- Progressive Muscular Dystrophy (1 open to new patients)
- Progressive Supranuclear Palsy (2 open to new patients)
- Prostate Cancer (6 open to new patients)
- Prosthesis (1 open to new patients)
- Prosthesis and Implants (1 open to new patients)
- Psilocybin (4 open to new patients)
- Psoriasis (2 open to new patients)
- Psychedelic Experiences (1 open to new patients)
- Psychosocial Functioning (1 open to new patients)
- Psychotic Disorders (2 open to new patients)
- Pulmonary Arterial Hypertension (4 open to new patients)
- Pulmonary Embolism (2 open to new patients)
- Pulmonary Hypertension (7 open to new patients)
- Quadriplegia (1 open to new patients)
- Racism (1 open to new patients)
- Relapsing-Remitting Multiple Sclerosis (1 open to new patients)
- Renal Cell Carcinoma (2 open to new patients)
- Respiratory Distress Syndrome (1 open to new patients)
- Retinitis Pigmentosa (1 open to new patients)
- Rett Syndrome (2 open to new patients)
- Rheumatoid Arthritis (2 open to new patients)
- Sarcoidosis (2 open to new patients)
- Sarcoma (2 open to new patients)
- Schizoaffective Disorder (2 open to new patients)
- Schizophrenia (4 open to new patients)
- Schwannoma (1 open to new patients)
- Scleroderma, Limited (1 open to new patients)
- Scoliosis (1 open to new patients)
- Sedentary Behavior (1 open to new patients)
- Self-management (1 open to new patients)
- Semantic Variant Primary Progressive Aphasia (1 open to new patients)
- Sepsis (1 open to new patients)
- Short Bowel Syndrome (1 open to new patients)
- Shoulder Instability (1 open to new patients)
- Sickle Cell Anemia (5 open to new patients)
- Skin Cancer/Melanoma (5 open to new patients)
- Skin Diseases (1 open to new patients)
- Sleep (2 open to new patients)
- Sleep Apnea (9 open to new patients)
- Sleep Disorders (12 open to new patients)
- Small Lymphocytic Lymphoma (3 open to new patients)
- Smoking Cessation (2 open to new patients)
- Social Psychology (1 open to new patients)
- Solid Malignancies (1 open to new patients)
- Solid Neoplasm (1 open to new patients)
- Solid Tumor (13 open to new patients)
- Spinal Cord Injury (6 open to new patients)
- Spinal Deformity (1 open to new patients)
- Spinal Fusion (1 open to new patients)
- Spinal Muscular Atrophy (1 open to new patients)
- Spinal Stenosis (1 open to new patients)
- Spine (1 open to new patients)
- Spine Fusion (1 open to new patients)
- Spine Tumor (1 open to new patients)
- Squamous Cell Carcinoma (4 open to new patients)
- Stargardt (1 open to new patients)
- Stargardt Disease (2 open to new patients)
- Steatohepatitis (2 open to new patients)
- Steinert (1 open to new patients)
- Steinert Disease (1 open to new patients)
- Stem Cell Transplant (4 open to new patients)
- STGD1 (1 open to new patients)
- Stomach Cancer (4 open to new patients)
- Stress (8 open to new patients)
- Stroke (6 open to new patients)
- Subarachnoid Hemorrhage (2 open to new patients)
- Subluxations (1 open to new patients)
- Substance Abuse (1 open to new patients)
- Suicidal Ideation (2 open to new patients)
- Surgery (2 open to new patients)
- Surgical Wound Infection (1 open to new patients)
- Survivorship (1 open to new patients)
- Systemic Sclerosis (2 open to new patients)
- Telangiectasia (1 open to new patients)
- Tetraplegia (2 open to new patients)
- Thalassemia (1 open to new patients)
- THC (1 open to new patients)
- Therapeutic Proteins (1 open to new patients)
- Thermal Burn (1 open to new patients)
- Thoracic Injury (1 open to new patients)
- Thoracic Tumors (1 open to new patients)
- Thyroid Cancer (1 open to new patients)
- Thyroid Eye Disease (1 open to new patients)
- Time Restricted Eating (1 open to new patients)
- Time Restricted Feeding (1 open to new patients)
- Tinnitus (1 open to new patients)
- Tobacco (3 open to new patients)
- Transcranial Direct Current Stimulation (1 open to new patients)
- Transcranial Magnetic Stimulation (6 open to new patients)
- Transitional Cell Carcinoma (1 open to new patients)
- Transplants (10 open to new patients)
- Transthyretin Amyloidosis (1 open to new patients)
- Trauma and Stressor Related Disorders (1 open to new patients)
- Traumatic Brain Injury (5 open to new patients)
- Trigeminal Neuralgia (1 open to new patients)
- Triple-Negative Breast Cancer (1 open to new patients)
- Type2diabetes (2 open to new patients)
- Ulcerative Colitis (7 open to new patients)
- Upper Gastrointestinal Hemorrhage (1 open to new patients)
- Ureteral Diseases (1 open to new patients)
- Urinary Bladder Tumor (1 open to new patients)
- Uveitis (1 open to new patients)
- Vaccine (1 open to new patients)
- Vaginal Stenosis (1 open to new patients)
- Vaginal Stricture (1 open to new patients)
- Vaping (1 open to new patients)
- Vascular Disease (2 open to new patients)
- Vascular Thrombosis (1 open to new patients)
- Vasospasm, Intracranial (1 open to new patients)
- Waldenstrom Macroglobulinemia (1 open to new patients)
- Weight Gain (1 open to new patients)
- Weight Loss (1 open to new patients)
- WetAMD (1 open to new patients)
- X-Linked Protoporphyria (1 open to new patients)
- Zinc Deficiency (1 open to new patients)