Acoustic Neuroma clinical trials at University of California Health
4 in progress, 2 open to eligible people
Innovative Trial for Understanding the Impact of Targeted Therapies in NF2
open to eligible people ages 12 years and up
This is a multi-arm phase II platform-basket screening study designed to test multiple experimental therapies simultaneously in patients with neurofibromatosis type 2 (NF2) with associated progressive tumors of vestibular schwannomas (VS), non-vestibular schwannomas (non-VS), meningiomas, and ependymomas. This Master Study is being conducted as a "basket" study that may allow people with multiple tumor types associated with NF2 to receive new drugs throughout this study. Embedded within the Master Study are individual drug substudies. - Investigational Drug Sub-study A: Brigatinib - Investigational Drug Sub-study B: Neratinib
at UCLA
Intraoperative Electrically-evoked ABRs in Patients Undergoing Vestibular Schwannoma Surgery
open to eligible people ages 18-99
This is a study of the feasibility of activating the auditory system by an electrode in direct contact with the cochlear nerve.
at UC Irvine
Phase 2 Clinical Trial of Crizotinib for Children and Adults With Neurofibromatosis Type 2 and Progressive Vestibular Schwannomas
Sorry, in progress, not accepting new patients
Subjects with Neurofibromatosis Type 2 (NF2) and progressive vestibular schwannoma (VS) will be treated with crizotinib administered orally. Crizotinib will be taken continuously until disease progression or unacceptable toxicity, in continuous treatment cycles of 28 days each, for a maximum of 12 cycles.
at UCLA
Study of RAD001 for Treatment of NF2-related Vestibular Schwannoma
Sorry, in progress, not accepting new patients
The purpose of the study is to determine if RAD001 treatment will shrink or slow the growth of the vestibular schwannoma(s) in Neurofibromatosis 2 (NF2) patients. Secondary objectives include determining if RAD001 treatment will improve hearing ability in NF2 patients. RAD001 is an oral drug that is approved by Food and Drug Administration (FDA) for other types of tumors, it is not approved by the FDA for treatment of NF2 related tumors.
at UCLA
Our lead scientists for Acoustic Neuroma research studies include Harrison M Lin, MD Marco Giovannini, MD, PhD John C Middlebrooks, PhD.
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