Adverse Childhood Experiences clinical trials at University of California Health
2 research studies open to eligible people
BLOOM: Boldly Living outdOOrs for Mental Health
open to eligible people ages 9-12
In 2019, the Office of the California Surgeon General launched the ACEs Aware Initiative in collaboration with the California Department of Health Care Services. This ambitious campaign aims to develop a network of care model of healthcare delivery that explicitly links health resources within communities to clinicians screening patients for ACEs. The ACEs Aware Initiative recognizes nature experiences as one of seven "stress busters." Indeed, California boasts many outdoor resources for clinicians to integrate into the network of care. Through a calming effect on the autonomic nervous system, providing a setting for supportive relationships to develop and physical activity to occur, time in nature may help California prevent, heal and treat ACEs and the clinical sequelae. As one of the most common psychiatric disorders in youth, anxiety remains one of the most important sequelae of ACEs. There is a gap in evidence evaluating nature-based programs for child mental health. This study will evaluate BLOOM [Boldly Living outdOOrs for Mental health], a new intervention which is a modified version of an existing nature-based curriculum called SHINE (Stay Healthy In Nature Everyday) curriculum currently in place at UCSF Benioff Children's Hospital Oakland, which takes youth and their families into nature once a month for stress relief. This new intervention mirrors SHINE except that it will be tailored to children ages 9-12 with a history of ACEs and current anxiety. This study will evaluate the benefits of a group intervention model, an independent nature-outing model, and a comparison to a wait-listed control group. Our goal is to provide a scalable model for low-cost mental health care to the California Department of Health Care Services.
at UCSF
THRIVE Study: Teaching Healthy Regulation in Individuals & Vulnerable Environments
open to eligible people ages 11-14
The goal of this 2-arm randomized control trial is to determine the impact of a community health worker delivered coaching intervention, GRIT, on preventing the early initiation of regular use of alcohol and cannabis among adversity-impacted adolescents ages 11-14 who do not regularly use alcohol or cannabis at baseline. The specific aims include: - Aim 1. Examine the effect of GRIT on preventing the early initiation of regular alcohol and cannabis use over time. - Aim 2. Examine the role of youth and caregiver self-regulation in mediating the effect of GRIT on adolescent rates of alcohol and cannabis use. Researchers will compare participants who are randomized to the GRIT intervention to an active control group, receiving a Digital Citizenship Curriculum, to see if those who participate in GRIT experience greater improvements in self-regulation and lower cardiometabolic risks. Participants will: - Be randomized to either receive the GRIT intervention (experimental group) or the Digital Citizenship Curriculum (active control group) - Complete 3 in-person visits at baseline, post-intervention, and 12-month post intervention - Complete HRV assessments using emWave Pro Plus and survey assessments on REDCap during in-person visits. - Participate in six 60-minute sessions conducted over 8 weeks via Zoom with an assigned community-health worker - Be invited to complete a booster session at 6-months post-intervention - Complete online measures at baseline, post-intervention, 6-month, and 12-month post-intervention
at UC Irvine UCLA
Our lead scientists for Adverse Childhood Experiences research studies include Nooshin Razani, MD MPH.
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