Aggressive Behavior in Fragile X Syndome clinical trials at University of California Health

The goal of this clinical trial is to learn if drug SRX246 works to treat irritability, agitation, aggression and self-injury (IAAS) behaviors in adult males with Fragile X Syndrome (FXS). It will also learn about the safety of drug SRX246. The main questions it aims to answer are: - Does drug SRX246 lower the number of times participants experience IAAS behaviors? - What medical problems do participants have when taking drug SRX246? Researchers will compare drug SRX246 to a placebo (a look-alike substance that contains no drug) to see if drug SRX246 works to treat IAAS behaviors. Participants will: - Take drug SRX246 or a placebo every day for up to 8 months - Have weekly checkups by phone or video to answer study questions - Have periodically scheduled home visits by nurses to conduct medical check-ups and tests - Keep a diary of their symptoms