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Anesthesia clinical trials at UC Health
7 in progress, 5 open to eligible people

  • Anesthetics and Analgesics in Children

    open to eligible people ages 2-17

    The purpose of this study is to characterize the pharmacokinetic (PK) and safety profile of anesthetics and analgesics in children and adolescents.

    at UCSF

  • Comparison of Depth of Sedation Performance Between SedLine and Comparator Device During General Anesthesia

    open to eligible people ages 18 years and up

    The primary objective is to compare the performance of Masimo's SedLine and the comparator's device systems during surgery. Relative accuracy of the individual depth of sedation indices will be compared.

    at UC Davis

  • Does Single Injection Adductor Canal Block Improve Postoperative Analgesia in Patients Receiving Periarticular Local Anesthesia Injections for Total Knee Arthroplasty?

    open to eligible people ages 18 years and up

    The purpose of the study is to determine the effect of a single injection adductor canal block (ACB) on pain scores within 24 hours post total knee arthroplasty (TKA).

    at UC Irvine

  • Esophageal Manometry During Recovery From Anesthesia: Pilot Study

    open to eligible people ages 18-70

    1. An intact pharyngoesophageal reflex is essential to protect the upper airway from aspiration of either mouth contents or regurgitated gastric refluxate. This reflex is essential at protecting the airway in all patients. 2. In patients, while under general anesthesia, it is postulated that an identifiable upper esophageal sphincter and esophageal peristalsis are not present. 3. With the cessation of general anesthetics, accompanied by the reversal of nerve block, normal pharyngoesophageal peristaltic activity correlates with awakening the patient from anesthesia. This would be identified by the performance of esophageal manometry. 4. A return of normal verbally stimulated pharyngoesophageal swallowing sequence accurately identifies a safe time to remove endotracheal tubes and/or reverse anesthesia. This verbally stimulated swallowing sequence correlated precisely with the return of objective pharyngoesophageal function.

    at UCSF

  • Regional Versus General Anesthesia for Promoting Independence After Hip Fracture

    “Which anesthesia is better for hip fracture surgery patients, regional block anesthesia or general anesthesia?”

    open to eligible people ages 50 years and up

    The purpose of this study is to find out if two types of standard care anesthesia are the same or if one is better for people who have hip fractures.

    at UC Davis

  • Assessment of Ventilatory Management During General Anesthesia for Robotic Surgery

    Sorry, in progress, not accepting new patients

    The aim of this study is to assess the incidence of postoperative pulmonary complications in patients undergoing mechanical ventilation during general anesthesia for robotic surgery, to characterize current practices of mechanical ventilation and to evaluate a possible association between ventilatory parameters and postoperative pulmonary complications.

    at UCSF

  • Cognitive Effects of Anesthesia on Children

    Sorry, in progress, not accepting new patients

    Anesthesia for more than 120 minutes given to children less than 2 years of age without coexisting diseases of the central nervous system or the heart cause long-term impairment of recognition memory.

    at UC Davis UCSF

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