Aneurysm clinical trials at University of California Health
22 in progress, 13 open to eligible people
Branched Aortic Arch Study
open to eligible people ages 18 years and up
This is a study to assess the safety and effectiveness of endovascular treatment of aortic aneurysms involving the proximal aortic arch. The investigational operation involves placing a stent-graft over the aortic aneurysm.
at UCSF
Citadel Embolization Device Study
open to eligible people ages 18-80
The purpose of this study is to gather safety and effectiveness data on Stryker Neurovascular's Next Generation Target Detachable Coil (hereafter referred to as the Citadel Embolization Device), when used with Target Detachable Coils, in the…
at UCSF
Endovascular Exclusion of Thoracoabdominal And/or Paravisceral Abdominal Aortic Aneurysm
open to eligible people ages 18 years and up
This is a study to assess the safety and effectiveness of endovascular treatment of thoracoabdominal (TAAA) and paravisceral abdominal (PVAAA) aortic aneurysms. The investigational operation involves placing a stent-graft over the aortic aneurysm.
at UCSF
Endurant Stent Graft System vs Excluder Endoprothesis: ADVANCE Trial
open to eligible people ages 20 years and up
The purpose of this trial is to generate clinical evidence related to key performance outcomes of Endurant II/IIs Stent Graft Systems verses Gore Excluder / Excluder Conformable AAA Endoprosthesis in subjects with Abdominal Aortic Aneurysms.…
at UC Davis UC Irvine UCSF
Endovascular Repair Of Ascending Aortic Pathologies
open to eligible people ages 18 years and up
The purpose of this study is to investigate the outcome of patients with pathologies of the ascending thoracic aorta (diseases in the great blood vessel or artery that leads away from the heart) including type A aortic dissection, retrograde type A…
at UCLA
Neurochecks on Sleep in Critically Ill Adults
open to eligible people ages 18-100
Background: Following acute brain injury (ABI), patients are monitored in the intensive care unit (ICU) where providers rely on frequent neurological examinations ("neurochecks") to assess for neurodeterioration. Serial neurochecks are part of…
at UCSD
JAGUAR Trial: ObJective Analysis to GaUge EVAR Outcomes Through Randomization
open to eligible people ages 21 years and up
Prospective, randomized, multi-center study designed to evaluate the outcomes of commercially available contemporary EVAR in a real-world population. Patients will be randomized into two device cohorts and compared across the primary endpoints.…
at UCSD
NEXUS Aortic Arch Clinical Study to Evaluate Safety and Effectiveness
open to eligible people ages 18 years and up
Prospective, non-randomized, multi-center clinical investigation of the NEXUS™ Aortic Arch Stent Graft System (NEXUSTM) for the treatment of thoracic aortic lesions involving the aortic arch with a proximal landing zone, native or previously…
at UCSD
Physician Modified Endograft For Complex Aortic Aneurysm Repair
open to eligible people ages 18 years and up
The physician modified endograft is intended for treating complex, pararenal, juxtarenal and thoracoabdominal aortic aneurysms requiring coverage of renal arteries, the superior mesenteric artery or the celiac trunk in high-risk patients who do not…
at UCSD
ShOrt neCK AAA RAndomized Trial - ESAR and FEVAR: SOCRATES
open to eligible people ages 18 years and up
The aim of this randomized study is to compare the safety and performance of EndoVascular Aneurysm Repair with ESAR using Endurant + Heli-FX™ EndoAnchor™ system and FEVAR using customizable grafts from Cook (Zenith Fenestrated Graft) and Terumo…
at UCSD
Treatment in Thoracic Aortic Aneurysm: Surgery vs Surveillance
open to eligible people ages 18-79
The ascending aorta conducts blood from the heart to the rest of the body. The ascending aorta can become enlarged, and the risk of tearing and rupturing becomes higher with larger aorta. When the ascending aorta tears or ruptures, the risk dying is …
at UCSF
Zenith® Fenestrated+ Clinical Study
open to eligible people ages 18 years and up
The Zenith® Fenestrated+ Endovascular Graft Clinical Study will assess the safety and effectiveness of the Zenith® Fenestrated+ Endovascular Graft (ZFEN+) in combination with the BeGraft Balloon-Expandable FEVAR Bridging Stent Graft System (BeGraft) …
at UCSD
Follow-up After Endovascular Repair of Abdominal Aortic Aneurysm
open to eligible people ages 18 years and up
To collect and analyze clinical follow-up data which can be used to assess the safety, efficacy, and durability of endovascular AAA repair with Zenith and Chuter-Gianturco stent-grafts.
at UCSF
BioVentrix Revivent TC™ System Clinical Study
Sorry, in progress, not accepting new patients
A prospective, multi-center, dual-arm pivotal study of the BioVentrix Revivent TC System, with 2:1 study vs. active concurrent control group allocation ratio. This study will include 126 patients of which 84 patients will be treated with the…
at UCLA UCSF
Stryker Surpass Evolve™ Flow Diverter System
Sorry, in progress, not accepting new patients
The primary objective of this study is to evaluate the safety and effectiveness of the Surpass™ Evolve Flow Diverter System in the treatment of unruptured, wide-neck intracranial aneurysms measuring ≤ 12 mm and located on the ICA or its branches
at UCLA
EVAS2 IDE Prospective, Multicenter, Single Arm Safety and Effectiveness Confirmatory Study
Sorry, in progress, not accepting new patients
Prospective, multicenter, single arm study with consecutive, eligible subject enrollment at each site. All subjects will undergo the Endovascular Aneurysm repair procedure with the Nellix System.
at UCLA
Infliximab Therapy for Dolichoectactic Vertebrobasilar Aneurysms
Sorry, accepting new patients by invitation only
Patients harboring dolichoectactic vertebrobasilar (DVB) aneurysms are at risk of suffering SAH, ischemic stroke, and/or brainstem compression and many patients are not offered invasive treatment due to the futility of existing surgical methods.…
at UCSF
Nectero EAST System Clinical Study
Sorry, currently not accepting new patients, but might later
The purpose of this randomized clinical trial is to treat patients with small to mid-sized abdominal aortic aneurysms (AAA), maximum diameter of 3.5 cm to 5.0 cm, using a locally delivered, single-dose endovascular treatment. The main question the…
at UCSF
Post-Approval Study of the TREO Abdominal Stent-Graft System
Sorry, not currently recruiting here
The purpose of this study is to determine the long-term performance of the TREO Abdominal Stent-Graft as a treatment for patients with Infrarenal Abdominal Aortic Aneurysms or Aorto-iliac Aneurysms.
at UCSD
RelayPro Thoracic Stent-Graft in Subjects With Thoracic Aortic Aneurysms and Penetrating Atherosclerotic Ulcers
Sorry, in progress, not accepting new patients
Investigate the safety and effectiveness of the RelayPro Thoracic Stent-Grafts in subjects with thoracic aortic aneurysms (TAA) and penetrating atherosclerotic ulcers (PAU) of the descending thoracic aorta.
at UC Irvine
ANCHOR (Aneurysm Treatment Using the Heli-FX™ EndoAnchor™ System Global Registry)
Sorry, in progress, not accepting new patients
The ANCHOR registry is a multi-center, post-market, non-interventional, non-randomized, prospective study. Subjects must sign an ICF prior to obtaining any study specific information. Subjects are eligible to be consented up to 30 days…
at UC Irvine UCLA
Zenith® Fenestrated Abdominal Aortic Aneurysm (AAA) Endovascular Graft Continued Access Study
Sorry, not accepting new patients
The Zenith®Fenestrated AAA Endovascular Graft Clinical Study is a clinical investigation approved by the US FDA to study the safety and effectiveness of the Zenith® Fenestrated AAA Endovascular Graft in the treatment of abdominal aortic and…
at UCSF
Our lead scientists for Aneurysm research studies include Elaine Tseng, MD John Lane, M.D. Daniel Cooke Eugene Golts, M.D. Warren Gasper Mahmoud Malas, MD Jade Hiramoto, MD Rodney A White, M.D. Joseph H Rapp, MD Jamie Labuzetta.
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