Cannabidiol clinical trials at University of California Health
11 in progress, 8 open to eligible people
Hemp-Derived, High Cannabidiol Product for Anxiety in Glioblastoma Patients
open to eligible people ages 18 years and up
Glioblastoma (GBM) is the most common malignant brain tumor among adults. As the diagnosis is generally considered terminal, patients with GBM often suffer from anxiety and other comorbid conditions, including depression, pain, and sleep…
at UCSF
Cannabidiol and Prolonged Exposure
open to eligible people ages 18 years and up
The trial will include a randomized control trial to evaluate the efficacy of using Cannabidiol (CBD), a non-intoxicating cannabinoid, as an adjunctive to Prolonged Exposure therapy (PE). The trial will compare PE + CBD to PE + placebo in a sample…
at UCSD
Cannabidiol for Reducing Cigarette Use
open to eligible people ages 18-65
The goal of this research is to evaluate the efficacy of cannabidiol (CBD) in reducing cigarette smoking. Although there are safe and effective treatments for smoking cessation, not everyone who attempts smoking cessation is successful, even with…
at UCLA
Cannabis Use, Cognition, and the Endocannabinoid System in HIV
open to eligible people ages 18-65
Understanding how co-morbidities in persons with HIV (PWH) such as substance use affect risk-taking, decision-making, and other cognitive behaviors is important given implications for everyday functioning and transmission risk. The high prevalence…
at UCSD
Cannabidiol (CBD) Versus Placebo as an Adjunct to Treatment in Early Psychosis
open to eligible people ages 16-30
This is an outpatient, single center, between-group, double blind, placebo controlled design. Approximately 120 adolescents and adult patients will be randomized to either have their treatment augmented with Cannabidiol Oral Solution (CBD) or with a …
at UCSD
Cannabidiol and Tetrahydrocannabinol on Microbiome and Neuroinflammation in HIV
open to eligible people ages 21-70
This study has the potential to contribute to a more complete understanding of the independent and combined effects of cannabis use and HIV on the brain and on inflammation. Such knowledge may inform future strategies for treating brain disease and…
at UCSD
Cannabidiol in Children, Adolescents, and Young Adults with Fragile X Syndrome
“Children and teens between 3 and 17 diagnosed with Fragile X syndrome may qualify for a clinical trial”
open to eligible people ages 3-29
This is a randomized, double-blind, placebo-controlled, multiple-center study, to assess the efficacy and safety of Cannabidiol administered as ZYN002 for the treatment of children, adolescent, and young adult patients with Fragile X Syndrome (FXS). …
at UC Davis
Role of CBD in Improving Alexithymia
open to eligible people ages 21 years and up
Given the treatments that are available today for HIV disease, people living with HIV (PLWH) can generally expect good medical outcomes. However, HIV is still a chronic disease and there are remaining barriers to achieving ideal health status and…
at UCSD
Extension to Assess the Long-Term Safety and Tolerability of ZYN002 in Children and Adolescents With FXS
Sorry, accepting new patients by invitation only
ZYN002 is a pharmaceutically manufactured Cannabidiol that is developed as a clear gel that can be applied to the skin (called transdermal delivery). The gel will be applied to clean, dry, intact skin of the shoulders and/or upper arms. Participants …
at UC Davis
Role of CBD in Regulating Meal Time Anxiety in Anorexia Nervosa
Sorry, in progress, not accepting new patients
No studies of cannabidiol (CBD) have focused on Anorexia Nervosa (AN). Dose, side effects, tolerability, acceptability of pure CBD in AN must be established. The current study is an important first step in the investigation of CBD for AN. Cannabis…
at UCSD
Cannabidiol in Sanfilippo Syndrome
Sorry, not yet accepting patients
The goal of this clinical trial is to test cannabidiol in Sanfilippo syndrome. The main questions it aims to answer are: 1) determine the safety of cannabidiol in Sanfilippo syndrome, and 2) explore the efficacy of cannabidiol in treating the…
at UCLA
Our lead scientists for Cannabidiol research studies include Guido K Frank, MD Kristin Cadenhead, MD Erin E Morgan, PhD Ronald J Ellis, MD, PhD Nicholas Butowski Arpi Minassian, Ph.D. Catherine R Ayers, PhD Brian Martis, MD Lynda E Polgreen Edythe D London, PhD.
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