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Cocaine Use clinical trials at UC Health
3 research studies open to eligible people

  • Occupational Therapy-Based Cognitive Rehabilitation of Cocaine Abusers: A Pilot Study

    open to eligible people ages 18-65

    This study integrates a model of occupational-therapy based cognitive rehabilitation as part of a comprehensive treatment plan for cocaine abusers. We hypothesize that cognitive impairment and quality of life would improve and that cocaine use would decrease in those participants receiving occupational-therapy based cognitive rehabilitation.

    at UCSF

  • Stimulant Oxytocin Study

    open to eligible people ages 18 years and up

    This study will investigate the effects of intranasal administration of oxytocin, a social neuropeptide, on reducing cocaine use, enhancing therapeutic engagement, and susceptibility to stress-induced relapse in Veterans with cocaine use disorder and enrolled in opioid replacement therapy (ORT) program for co-occurring opioid use disorder (OUD).

    at UCSF

  • Treatment With Lorcaserin for Cocaine Use: The TLC Study

    open to eligible males ages 18-65

    This project is a placebo-controlled, double-blind randomized trial evaluating the feasibility, tolerability, acceptability and adherence for lorcaserin among actively using, men who have sex with men (MSM) with cocaine use disorders.The study will enroll 45 individuals who will randomly be assigned to either the treatment (lorcaserin) arm or the placebo arm, to be taken twice a day for 12 weeks.

    at UCSF