Critical Limb Ischemia clinical trials at UC Health
3 studies in progress, 2 open to new patients
Intima Versus Adventitia Drug Delivery to Elucidate Mechanisms of Restenosis: Magnetic Resonance Imaging
open to eligible people ages 35 years and up
This is a prospective, multicenter, randomized trial to determine the mechanisms of vascular healing. The study will evaluate subjects with peripheral artery disease (PAD) who require an endovascular intervention of the femoro-popliteal (SFA) artery to restore blood flow to the leg.
Study of best available surgical treatment/best available endovascular treatment in adults with CLI, eligible for both treatments
“Is angiplasty (endovascular) or bypass graft (open surgery) best for critical limb ischemia (CLI)?”
open to eligible people ages 18 years and up
This study will compare the effectiveness of best available surgical treatment with best available endovascular treatment in adults with critical limb ischemia (CLI) who are eligible for both treatment options.
at UCLA UCSF UC Irvine UCSD UC Davis
Safety and Efficacy Study of Autologous Concentrated Bone Marrow Aspirate (cBMA) for Critical Limb Ischemia (CLI)
Sorry, in progress, not accepting new patients
This trial will evaluate the safety and efficacy of concentrated bone marrow aspirate (cBMA) to prevent or delay major amputation and/or death in subjects with critical limb ischemia (CLI) due to severe peripheral arterial disease (PAD).
at UC Davis