Skip to main content

Dystonia clinical trials at University of California Health

4 research studies open to eligible people

Showing trials for
  • The Motor Network in Parkinson's Disease and Dystonia: Mechanisms of Therapy

    open to eligible people ages 21-75

    This is an exploratory pilot study to identify neural correlates of specific motor signs in Parkinson's disease (PD) and dystonia, using a novel totally implanted neural interface that senses brain activity as well as delivering therapeutic stimulation. Parkinson's disease and isolated dystonia patients will be implanted unilaterally or bilaterally with a totally internalized bidirectional neural interface, Medtronic Summit RC+S. This study includes three populations: ten PD patients undergoing deep brain stimulation in the subthalamic nucleus (STN), ten PD patients with a globus pallidus (GPi) target and five dystonia patients. All groups will test a variety of strategies for feedback-controlled deep brain stimulation, and all patients will undergo a blinded, small pilot clinical trial of closed-loop stimulation for thirty days.

    at UCSF

  • Abbott DBS Post-Market Study of Outcomes for Indications Over Time

    open to all eligible people

    The purpose of this international study is to evaluate long-term safety and effectiveness of Abbott deep brain stimulation (DBS) systems for all indications, including Parkinson's disease, essential tremor or other disabling tremor and dystonia.

    at UC Davis

  • Deep Brain Stimulation (DBS) Retrospective Outcomes Study

    open to all eligible people

    The primary objective of this study is to characterize real-world clinical outcomes of Deep Brain Stimulation (DBS) using retrospective review of de-identified patient records.

    at UCSF

  • Studies of the Variable Phenotypic Presentations of Rapid-Onset Dystonia Parkinsonism and Other Movement Disorders

    open to eligible people ages 18 months and up

    The purposes of this study are to identify persons with rapid-onset dystonia-parkinsonism (RDP) or mutations of the RDP gene, document prevalence of the disease, and map its natural history.

    at UC Davis

Our lead scientists for Dystonia research studies include .

Last updated: