Endocrine System Diseases clinical trials at University of California Health

2 in progress, 0 open to eligible people

Showing trials for

  • Linsitinib in Subjects With Active, Moderate to Severe Thyroid Eye Disease (TED)

    Sorry, in progress, not accepting new patients

    The overall objective is to study the safety, pharmacokinetics and efficacy of linsitinib (a small molecule IGF-1R inhibitor) administered orally twice daily (BID) vs. placebo, at 24 weeks in the treatment of subjects with active, moderate to severe thyroid eye disease (TED).

    at UCLA UCSD

  • Eneboparatide (AZP-3601) in Patients With Chronic Hypoparathyroidism

    Sorry, in progress, not accepting new patients

    This study is investigating the safety and efficacy of eneboparatide (AZP-3601) in patients with chronic hypoparathyroidism (cHP). During the first 24 weeks of the trial, participants will be randomized to receive eneboparatide or placebo. Study treatment is blinded: patients and doctors will not know which group each patient has been randomized to. All patients will start with a fixed dose of study treatment (eneboparatide or placebo), administered subcutaneously with a pre-filled pen. Study treatment will be individually titrated. After completion of the first 24 weeks, patients will be treated in the open label extension part of the study for 132 weeks. During this phase, all patients (including patients that were in the placebo group) will receive eneboparatide.

    at UCLA