Fecal Incontinence clinical trials at University of California Health

2 in progress, 0 open to eligible people

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  • Iltamiocel Compared to Placebo for Chronic Fecal Incontinence in Females With Obstetric Injury

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    This study evaluates the efficacy and safety of a single injection of iltamiocel (300 x 10^6 cells) compared to a placebo in the reduction of fecal incontinence episode frequency in adult female participants with chronic fecal incontinence and a history of obstetric anal sphincter injury. Half of the participants will receive iltamiocel (injections with cells) and the other half will receive placebo.

    at UC Irvine UCSD UCSF

  • Bowel Continence Across the Lifespan in People With Spina Bifida

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    The goal of this observational study is to learn how different enema programs affect bowel control in children and adults with spina bifida. An enema program involves putting liquid into the large intestine (colon) to help someone poop. The main questions it aims to answer are: 1. How well do different enema programs prevent bowel accidents? 2. How do these enema programs affect independence, bowel symptoms, and quality of life? Researchers will compare two types of enema programs to see which works better and is easier for participants to manage. Participants starting a new enema program will answer online survey questions at 3 different timepoints over the course of 1 year.

    at UCSF

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