Hearing Loss clinical trials at University of California Health
7 in progress, 2 open to eligible people
DB-OTO, an Adeno-associated Virus (AAV) Based Gene Therapy, in Children/Infants With Hearing Loss Due to Otoferlin Mutations
open to eligible people ages up to 17 years
Regeneron is conducting a study of an investigational new drug called DB-OTO. DB-OTO is a gene therapy that is being developed to treat children who have hearing loss due to changes in the otoferlin gene. The purpose of this study is to: - Learn…
at UCLA
Preschool Hearing Screening
open to eligible people ages 2-6
Children who are deaf or hard-of-hearing (D/HH) are at risk of speech and language delays, which can be mitigated through early identification and intervention. Identifying hearing loss (HL) during preschool is crucial, but the most effective…
at UCSF
Treatment for Medulloblastoma Using Sodium Thiosulfate to Reduce Hearing Loss
Sorry, currently not accepting new patients, but might later
This phase III trial tests two hypotheses in patients with low-risk and average-risk medulloblastoma. Medulloblastoma is a type of cancer that occurs in the back of the brain. The term, risk, refers to the chance of the cancer coming back after…
at UCLA UCSF
Cochlear Implant With Dexamethasone Eluting Electrode Array
Sorry, in progress, not accepting new patients
An evaluation of Cochlear's cochlear implant electrode array which passively elutes dexamethasone for a defined period of time to help reduce inflammatory responses.
at UCLA
CT Guided CI Programming
Sorry, in progress, not accepting new patients
The current standard of care for cochlear implants (CI) does not address the significant pitch-place mismatch that is inherent in cochlear implantation (see detailed description below). The present study uses postoperative Flat Panel (higher…
at UCSF
Valganciclovir for Cytomegalovirus Infected Hearing Impaired Infants
Sorry, in progress, not accepting new patients
The overall goal of this study is to determine the clinical benefit and safety of antiviral therapy for asymptomatic congenital cytomegalovirus (cCMV) infected hearing-impaired infants. We will conduct a multi-center double-blind randomized…
at UCSF
Teletherapy in Children Who Are Deaf and Hard of Hearing
Sorry, in progress, not accepting new patients
This study seeks to determine the effectiveness of speech/language teletherapy to address disparities in speech and language outcomes in children who are deaf or hard-of-hearing (D/HH). The investigators will enroll D/HH children aged 0-27 months.…
at UCSF
Our lead scientists for Hearing Loss research studies include Akira Ishiyama, MD Charles J Limb, MD Satiro De Oliveira, MD Dylan K Chan, MD, PhD.
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