Hemorrhage clinical trials at University of California Health

• Cold Stored Platelet in Hemorrhagic Shock

  Sorry, not yet accepting patients

  The Cold Stored Platelet Early Intervention in Hemorrhagic Shock (CriSP-HS) trial is a proposed 3 year, open label, multi-center, randomized trial designed to determine the feasibility, efficacy, and safety of urgent release cold stored platelets (CSP) in patients in hemorrhagic shock. Patients will be randomized to receive either standard care or early infusion of urgent release cold stored platelets (CSP). The proposed pilot study will utilize 5 level-1 trauma centers from within the LITES network and will enroll approximately 200 patients. The primary outcome for the pilot trial is feasibility, with principal secondary clinical outcome of 24 hour mortality.

  at UCSF

• Quantra QStat in Trauma and Liver Transplant

  Sorry, accepting new patients by invitation only

  This is a multi-center prospective, observational study of the Quantra System with the QStat Cartridge in trauma patients and patients undergoing liver transplant.

  at UCSF

• Traumatic Injury Clinical Trial Evaluating Tranexamic Acid in Children: An Efficacy Study

  Sorry, not yet accepting patients

  Trauma is the leading cause of death and disability in children in the United States. The objective of this study is to evaluate the benefits and harms of tranexamic acid (TXA; a drug that stops bleeding) in severely injured children with hemorrhagic brain and/or torso injuries. Using thromboelastography, we will measure baseline fibrinolysis to assess for treatment effects of TXA at different levels of fibrinolysis.

  at UC Davis

Last updated: September 9, 2021