IgA Nephropathy clinical trials at University of California Health
5 in progress, 4 open to eligible people
BION-1301 in Adults With IgA Nephropathy
open to eligible people ages 18 years and up
Safety and Efficacy of BION-1301 in Adults with IgA Nephropathy
at UCSF
Sefaxersen (RO7434656) in Participants With Primary Immunoglobulin A (IgA) Nephropathy at High Risk of Progression
open to eligible people ages 18 years and up
The purpose of this study is to evaluate the efficacy, safety, and pharmacokinetics of sefaxersen (RO7434656), a novel Antisense Oligonucleotide (ASO) therapy in participants with primary IgA nephropathy (IgAN) who are at high risk of progressive kidney disease despite optimized supportive care.
at UCLA
Atacicept in Subjects with IgA Nephropathy
open to eligible people ages 18 years and up
A Phase 3 Study with Atacicept in Subjects With IgA Nephropathy (ORIGIN 3)
at UCLA
Ravulizumab in Immunoglobulin A Nephropathy (IgAN)
open to eligible people ages 18 years and up
The primary objective of this study to evaluate efficacy of ravulizumab compared with placebo on proteinuria reduction and change in eGFR in adult participants with IgAN who are at risk of disease progression.
at UCLA UCSF
LNP023 in Primary IgA Nephropathy Patients
Sorry, in progress, not accepting new patients
The study is designed as a multicenter, randomized, double-blind, placebo controlled study to demonstrate the superiority of iptacopan (LNP023) at a dose of 200 mg b.i.d. compared to placebo on top of maximally tolerated ACEi or ARB on reduction of proteinuria and slowing renal disease progression in primary IgA Nephropathy patients.
at UCLA
Our lead scientists for IgA Nephropathy research studies include Mrinalini Sarkar, MD Anjay Rastogi, MD, PhD.
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