IgA Nephropathy clinical trials at University of California Health

6 in progress, 3 open to eligible people

Showing trials for

  • BION-1301 in Adults With IgA Nephropathy

    open to eligible people ages 18 years and up

    Safety and Efficacy of BION-1301 in Adults with IgA Nephropathy

    at UCSF

  • Ravulizumab in Immunoglobulin A Nephropathy (IgAN)

    open to eligible people ages 18 years and up

    The primary objective of this study to evaluate the efficacy of ravulizumab compared with placebo to reduce proteinuria and slow the rate of eGFR decline in adult participants with IgAN who are at risk of disease progression.

    at UCLA UCSF

  • Ravulizumab in Proliferative Lupus Nephritis (LN) or Immunoglobulin A Nephropathy (IgAN)

    open to eligible people ages 18-75

    The objectives of this study are to evaluate the safety and efficacy of ravulizumab administered by intravenous (IV) infusion compared to placebo and demonstrate proof-of-concept of the efficacy of terminal complement inhibition in participants with LN (LN Cohort) or IgAN (IgAN Cohort).

    at UCLA

  • Atrasentan in Patients With IgA Nephropathy

    Sorry, in progress, not accepting new patients

    The ALIGN Study is a phase 3, double-blind, placebo-controlled study to compare the efficacy and safety of atrasentan to placebo in patients with IgA nephropathy (IgAN) at risk of progressive loss of renal function.

    at UCLA

  • Atrasentan in Patients With Proteinuric Glomerular Diseases

    Sorry, in progress, not accepting new patients

    The AFFINITY Study is a phase 2, open-label, basket study to evaluate the efficacy and safety of atrasentan in patients with proteinuric glomerular disease who are at risk of progressive loss of renal function.

    at UCLA

  • LNP023 in Primary IgA Nephropathy Patients

    Sorry, in progress, not accepting new patients

    The study is designed as a multicenter, randomized, double-blind, placebo controlled study to demonstrate the superiority of iptacopan (LNP023) at a dose of 200 mg b.i.d. compared to placebo on top of maximally tolerated ACEi or ARB on reduction of proteinuria and slowing renal disease progression in primary IgA Nephropathy patients.

    at UCLA

Our lead scientists for IgA Nephropathy research studies include .

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