Lewy Body Dementia clinical trials at University of California Health
5 in progress, 1 open to eligible people
North American Prodromal Synucleinopathy Consortium Stage 2
open to eligible people ages 18 years and up
This study will enroll participants with idiopathic REM sleep behavior disorder (RBD) and healthy controls for the purpose of preparing for a clinical trial of neuroprotective treatments against synucleinopathies.
at UCLA
Parkinson's And Zoledronic Acid
Sorry, in progress, not accepting new patients
This home-based study is a randomized (1:1) placebo-controlled trial of a single infusion of zoledronic acid-5 mg (ZA) for the prevention of fractures in men and women aged 60 years and older with Parkinson's disease and parkinsonism with at least 2 years of follow-up. A total of 2650 participants will be enrolled and randomized in the United States. Participants, follow-up outcome assessors, and study investigators will be blinded to assigned study treatment. This trial is funded by the National Institute of Aging.
at UC Davis UC Irvine UCLA UCSF
Diagnostic Test for Dementia With Lewy Bodies
Sorry, in progress, not accepting new patients
The Syn-D Study will be evaluating α-synuclein in patients with suspected MCI-AD and MCI-DLB. Using a simple diagnostic test will improve clinical accuracy in diagnosing, earlier diagnosis, and distinguish between neurodegenerative diseases.
at UCSD
Environmental and Reproductive Health Risk for Lewy Body Dementia
Sorry, in progress, not accepting new patients
The goal of this survey study is to identify environmental, occupational and reproductive health risk factors for Lewy body dementia, which includes Parkinson's disease dementia and dementia with Lewy bodies. Participants will complete a one-time survey online or over the phone that includes questions on environmental, occupational factors they may have been exposed to and on medical history including reproductive health. Researchers will then compare the responses of people with Lewy body dementia and people without Parkinson's or memory/thinking problems to see which factors play a role in Lewy body dementia. Identifying risk factors can guide future treatment efforts and provide more insight to this dementia.
at UCSD
North American Prodromal Synucleinopathy Consortium
Sorry, accepting new patients by invitation only
This study will enroll participants with idiopathic rapid eye movement (REM) sleep behavior disorder (RBD), for the purpose of preparing for a clinical trial of neuroprotective treatments against synucleinopathies.
at UCLA
Our lead scientists for Lewy Body Dementia research studies include Alon Avidan, MD, MPH.