Macular Edema clinical trials at University of California Health
6 in progress, 3 open to eligible people
A Study of Experimental Treatment With Micropulse for Diabetic Macular Edema (build-up of fluid in the eye)
“This study will test the effect of using the subthreshold micropulse diode laser (SML).”
open to eligible people ages 18 years and up
Diabetic retinopathy is one of the most common complications of diabetes and diabetic macular edema (DME) is one of the most common causes of vision loss in diabetes. The purpose of this study is to determine if early intervention with micropulse laser treatment in eyes with good visual acuity (20/32 or better) will improve or stabilize vision loss due to the complications of diabetic macular edema.
at UC Davis
A Study to Investigate RO7200220 in Combination With Ranibizumab in Diabetic Macular Edema
open to eligible people ages 18 years and up
Study BP43464 is a phase II, multicenter, randomized, double-masked active comparator-controlled study designed to assess the efficacy, safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of RO7200220 in combination with, anti-vascular endothelial growth factor (VEGF) inhibitor, ranibizumab compared with ranibizumab alone in participants with diabetic macular edema. Only one eye will be chosen as the study eye. The duration of the study will be 76 weeks.
at UCLA
A Study to Investigate RO7200220 in Diabetic Macular Edema
open to eligible people ages 18 years and up
Study BP43445 is a phase II, multicenter, randomized, double-masked, active comparator-controlled study to investigate the efficacy, safety, tolerability, pharmacokinetics, and pharmacodynamics of RO7200220 administered intravitreally in participants with diabetic macular edema. Only one eye will be chosen as the study eye. The duration of the study will be up to 76 weeks.
at UCLA
A Trial to Evaluate the Efficacy, Durability, and Safety of KSI-301 Compared to Aflibercept in Participants With Diabetic Macular Edema (DME)
Sorry, in progress, not accepting new patients
This Phase 3 study will evaluate the efficacy, durability, and safety of KSI-301 compared to aflibercept in participants with treatment-naïve DME.
at UCSD
This Study Will Evaluate the Efficacy, Safety, and Pharmacokinetics of the Port Delivery System With Ranibizumab in Participants With Diabetic Macular Edema Compared With Intravitreal Ranibizumab
Sorry, in progress, not accepting new patients
This study will evaluate the efficacy, safety, and pharmacokinetics of the Port Delivery System with Ranibizumab (PDS) in Participants with Diabetic Macular Edema (DME) when treated every 24 weeks (Q24W) compared with intravitreal ranibizumab 0.5 mg every 4 weeks (Q4W).
at UCSF
Predicting Diabetic Retinopathy From Risk Factor Data and Digital Retinal Images
Sorry, in progress, not accepting new patients
The objective of this study is to compare the results of a deep learning approach to diabetic retinopathy assessment with results from (1) an in-person examination with an ophthalmologist, and (2) the assessments of optometrists involved in a teleretinal screening program.
at UCLA
Our lead scientists for Macular Edema research studies include Glenn Yiu, MD, PhD.
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