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Metabolic Acidosis clinical trials at University of California Health

2 in progress, 1 open to eligible people

Showing trials for
  • Sodium Bicarbonate and Mitochondrial Energetics in Persons With CKD

    open to eligible people ages 21-85

    Skeletal muscle metabolic health is critical for mobility and an underrecognized target of metabolic acidosis in chronic kidney disease. Impaired muscle mitochondrial metabolism underlies poor physical endurance increasing the risk of mobility disability. The proposed project will use precise in vivo tools to study the pathophysiology of poor physical endurance in a clinical trial treating metabolic acidosis among persons living with chronic kidney disease.

    at UC Davis

  • Adding Urea to the Final Dialysis Fluid

    Sorry, not yet accepting patients

    At times patients with advanced renal failure present with severe hyperkalemia or acidosis and very high serum blood urea nitrogen (BUN) concentrations. These patients cannot be dialyzed aggressively as the lowering of serum BUN may results in disequilibrium syndrome but on the other hand they need aggressive dialysis in order to lower their serum potassium or fix their severe acidosis. If one is able to add urea to the dialysis fluid, one can prevent the rapid lowering of serum BUN and osmolality at the same time as doing aggressive dialysis to lower serum potassium and/or fix the metabolic acidosis.

    at UCSF

Our lead scientists for Metabolic Acidosis research studies include .

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