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Multiple System Atrophy clinical trials at University of California Health

4 in progress, 3 open to eligible people

Showing trials for
  • A Study of Lu AF82422 in Participants With Multiple System Atrophy

    open to eligible people ages 40-75

    To find out the effect of Lu AF82422 on disease progression in participants with multiple system atrophy.

    at UCSD UCSF

  • GDNF Gene Therapy for Multiple System Atrophy

    open to eligible people ages 35-75

    The objective of this randomized, double-blinded, placebo-controlled Phase 1 investigation is to evaluate the safety and potential clinical effect of AAV2-GDNF delivered to the putamen in subjects with either a possible or probable diagnosis of Multiple System Atrophy.

    at UC Irvine

  • Trial of Parkinson's And Zoledronic Acid

    open to eligible people ages 60 years and up

    This home-based study is a randomized (1:1) placebo-controlled trial of a single infusion of zoledronic acid-5 mg (ZA) for the prevention of fractures in men and women aged 60 years and older with Parkinson's disease and parkinsonism with at least 2 years of follow-up. A total of 3500 participants will be enrolled and randomized in the United States. Participants, follow-up outcome assessors, and study investigators will be blinded to assigned study treatment. This trial is funded by the National Institute of Aging.

    at UC Davis UC Irvine UCLA UCSF

  • North American Prodromal Synucleinopathy Consortium

    Sorry, accepting new patients by invitation only

    This study will enroll participants with idiopathic rapid eye movement (REM) sleep behavior disorder (RBD), for the purpose of preparing for a clinical trial of neuroprotective treatments against synucleinopathies.

    at UCLA

Our lead scientists for Multiple System Atrophy research studies include .

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