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Oropharyngeal Dysphagia clinical trials at UC Health
4 in progress, 3 open to new patients

  • A Study of Continuous Positive Airway Pressure (CPAP) to Improve Swallow Function After Total Laryngectomy

    “A Continuous Positive Airway Pressure (CPAP) machine can improve swallow function if you've had a total Laryngectomy.”

    open to eligible people ages 18 years and up

    Investigator initiated prospective study to determine whether use of Continuous Positive Airway Pressure (CPAP) can improve the swallow function in patients who underwent total laryngectomy and are experiencing difficulty swallowing

    at UC Davis

  • Autologous Muscle Derived Cells for Gastro-Intestinal Repair (AMDC-GIR) for Tongue Dysphagia

    open to eligible people ages 18 years and up

    The primary objective of this study is to evaluate the safety of Autologous Muscle Derived Cells for Gastro-Intestinal Repair (AMDC-GIR) during the 12 months following treatment of tongue dysphagia in male and female patients who have undergone surgery and/or chemo- and/or radiotherapy for squamous cell cancer of the oropharynx.

    at UC Davis

  • Study looking at safety and efficacy of the Swallow Expansion Device (SED) for improvement of severe swallowing issues

    “Can the Swallow Expansion Device (SED) treat severe dysphagia?”

    open to eligible people ages 18 years and up

    Biomedical devices, such as artificial joints and pacemakers, are accepted and commonly used in medicine. While great progress in biomedical devices has been made for many other disorders, there is currently no device available to assist with the act of deglutition. The investigators have developed a biomedical device (Swallow Expansion Device, SED) that assists with swallowing by mechanically opening the upper esophageal sphincter and allowing food and liquid to safely enter the esophagus. The SED has proven safe in cadaver and live animal studies (Belafsky, 2010).

    at UC Davis

  • A Study of Negative Pressure Suction to Reduce Aspiration (inhaling food into lungs) Oropharyngeal Dysphagia (swallowing disorder)

    “An ear nose and throat study for people with stomach tubes”

    Sorry, in progress, not accepting new patients

    This is an investigator initiated prospective study to determine whether the use of a negative pressure suction in the hypopharynx will reduce the amount of aspiration during Video Fluoroscopic Swallowing Exam (VFSE) among patients with oropharyngeal dysphagia.

    at UC Davis

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