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Overactive Bladder clinical trials at University of California Health

7 in progress, 5 open to eligible people

Showing trials for
  • Real World Study of eCoin for Urgency Urinary Incontinence: Post Approval Evaluation (RECIPE)

    open to eligible people ages 18 years and up

    A prospective, multicenter, single-arm study to evaluate the safety and effectiveness of the eCoin® implanted tibial nerve stimulator in subjects with urgency urinary incontinence (UUI).

    at UC Irvine

  • Oxybutynin for Post-surgical Bladder Pain and Urgency

    open to eligible people ages 4-8

    Bladder pain and urgency are common after bladder surgery. The objective is to determine if transdermal administration is superior to oral administration in alleviating pain and urgency.

    at UC Davis

  • CAN-Stim Compared to SNS in Treatment of Urinary Urgency Incontinence With Wireless Neuromodulation Technology

    open to eligible people ages 18 years and up

    This is a prospective, randomized, controlled, multi-center, study in which 150 evaluable subjects will be randomized 1:1 to receive either a Protect CAN-Stim or SNS InterStim® system. Subjects from both groups will immediately start with therapy. The primary endpoint is a ≥ 50% reduction in number of incontinence episodes associated with urgency at the 3-month visit, with additional measurements assessed at 14 days, 1, 6, 9 and 12-months.

    at UC Irvine

  • TReating Incontinence for Underlying Mental and Physical Health

    open to eligible females ages 60 years and up

    The TRIUMPH study is a randomized, double-blinded, 3-arm, parallel-group trial designed to compare the effects of anticholinergic bladder therapy versus a) beta-3-adrenergic agonist bladder therapy and b) no bladder pharmacotherapy on cognitive, urinary, and other aging-related functional outcomes in ambulatory older women with urgency-predominant urinary incontinence and either normal or mildly impaired cognitive function at baseline.

    at UCSF

  • Wearables for the Bladder: an In-home Treatment Feasibility Pilot Study

    open to eligible females ages 18-80

    The goal is to investigate the feasibility and effects of adding "wearables for the bladder" devices to conventional pelvic floor physical therapy (PFPT) to bladder function, in people with multiple sclerosis (MS).

    at UCSF

  • BlueWind RENOVA iStim™ System for the Treatment of OAB

    Sorry, not currently recruiting here

    The OASIS study is prospective, interventional, multi-center study to evaluate the safety and efficacy of the BlueWind RENOVA iStim™ implantable tibial neuromodulation System for the treatment of patients diagnosed with overactive bladder.

    at UC Irvine

  • Intradetrusor Botulinum Toxin A for OAB Via 1 Versus 10 Injections: A Randomized Clinical Trial

    Sorry, in progress, not accepting new patients

    Patients with either overactive bladder (OAB) or urgency urinary incontinence (UUI) with be randomized (like a flip of a coin) to receive 100 units of bladder Botox® at either one injection site or ten injection sites. Efficacy and patient satisfaction will be measured by questionnaires.

    at UC Irvine

Our lead scientists for Overactive Bladder research studies include .

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