Paresis clinical trials at University of California Health

2 in progress, 0 open to eligible people

Showing trials for

  • Hand Rehabilitation Study for Stroke Patients

    Sorry, in progress, not accepting new patients

    The purpose of this study is to find out what are the best settings for applying electrical nerve stimulation over the skin for the short-term improvement of hand dysfunction after a stroke. The ultimate goal is to some day design an effective long-term training program to help someone recovery their ability to use their hands and function independently at home and in society. In order to know how to apply electrical nerve stimulation to produce a good long-term effect on hand dysfunction, we first need to know how to make it work best in the short-term, and improve our understanding of for whom it works and how it works.We will use a commercially available transcutaneous electrical nerve stimulation (TENS) unit to gently apply electrical nerve stimulation over the skin of the affected arm. This is a portable, safe and easy to use device designed for patients to operate in their homes.

    at UCSF

  • Improving Arm Function Using Wearable Exoskeletons

    Sorry, not yet accepting patients

    The goal of this clinical trial is to compare arm and hand function with and without assistance from a wearable exoskeleton in individuals with neurological injury from a single stroke. The main questions it aims to answer are: - Can a portable (i.e., body-mounted) shoulder exoskeleton increase the reachable workspace of an individual after stroke? - Can shoulder assistance from a body-mounted exoskeleton improve hand function after stroke? - Does shoulder assistance from a body-mounted exoskeleton lead to changes in functional use of the impaired limb at home? Participants will perform tasks with and without assistance from a portable exoskeleton, including: - maximal area sweeps in each of three directional planes (sagittal, frontal, transverse). - simultaneous wrist and finger extension while attempting to pick up objects of varying size from the Action Research Arm Test (ARAT), Wolf Motor Function Test (WMFT), and Box and Blocks (BBT) test kits. - standardized clinical assessments in a laboratory setting that have been shown to correlate with functional performance of activities of daily living including WMFT, ARAT, and BBT. - a Motor Activity Log (MAL) based on activity performed in the past week as a baseline, before wearing the exoskeleton at home for a period of 1-2 hours per day for at least 5 days. - a System Usability Scale and a second MAL corresponding with the activities performed while wearing the exoskeleton during the at-home phase. Researchers will compare functional ability measures with and without wearing the portable shoulder exoskeleton to see if the assistance improves functional performance in the arm and/or hand.

    at UC Irvine

Our lead scientists for Paresis research studies include .

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