Pollution Related Respiratory Disorder clinical trials at University of California Health
1 in progress, 0 open to eligible people
Innate Immunity in Ozone-induced Airway Inflammation in COPD
Sorry, in progress, not accepting new patients
Chronic obstructive pulmonary disease (COPD) is the third leading cause of death in the United States. Patients with COPD are routinely exposed to indoor and outdoor air pollution, which appears to cause escalation of their respiratory symptoms, a process called exacerbation, with resulting need to seek medical attention. This research plan proposes to evaluate the impact of lung immune cells in susceptibility to develop exacerbation through an experimental model of inhalational exposure using ambient levels of a component of air pollution (ozone) in COPD patients and longitudinal sampling of their lung immune cells.
Our lead scientists for Pollution Related Respiratory Disorder research studies include Mehrdad Arjomandi, M.D..