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Port-Wine Stain clinical trials at UC Health
2 in progress, 1 open to new patients

  • Novel Treatment for Port Wine Stain Birthmarks

    open to eligible people ages 18 years and up

    Port wine stains Birthmark are congenital, progressive vascular malformations of the skin that occur in approximately 0.7% of newborns. Approximately 1.5 million individuals in the United States and 32 million people worldwide have Port wine stains birthmarks. Two-thirds of these malformations occur on the face. Personality development of virtually all patients is adversely affected as a result of the negative reaction of others to a "marked" person. Detailed studies have documented lower self-esteem and difficulties with interpersonal interactions in Port wine stains patients. Port wine stains are initially flat and red, but with time, they tend to darken to purple and become thickened as vascular nodules develop. This thickening occurs in approximately two-thirds of lesions and further disfigures the facial features of many patients.

    at UC Irvine

  • Pathogenic Mechanisms of Port Wine Stain and Repository of Port Wine Stain Biopsy Samples

    Sorry, in progress, not accepting new patients

    The purpose of this study is to investigate the pathogenic mechanisms of Port Wine Stain, collect biopsy samples and blood samples to characterize exosomes and metabolites from Port Wine Stain.

    at UC Irvine