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Pregnancy clinical trials at University of California Health

29 in progress, 13 open to eligible people

Showing trials for
  • Anticoagulation Profile in Pregnant Women Treated with Three Times a Day of Low Molecular Weight Heparin (LMWH)

    open to eligible females ages 18 years and up

    Pregnancy is associated with a increased risk of developing blood clots. There is nearly a 5 times greater risk of developing a blood clot in pregnancy. Lovenox is a medication that helps to prevent the body from developing clots. It is safe to use…

    at UC Irvine

  • DETERMINE: Detemir vs NPH

    open to eligible people ages 18 years and up

    The purpose of the study is to compare rates of neonatal hypoglycemia with maternal NPH vs determir use.

    at UCLA

  • Two Aspirin Doses for Prevention of Hypertensive Disorders of Pregnancy: ASPIRIN TRIAL

    open to eligible females ages 14-35

    The overall goal of this large, pragmatic, comparative effectiveness trial is to test the hypothesis that among at-risk individuals, 162 mg/day aspirin is superior to 81 mg/day in preventing Hypertensive disorders of pregnancy (HDP), and that there…

    at UCSF

  • Engaging Mothers & Babies; Reimagining Antenatal Care for Everyone (EMBRACE) Study

    open to eligible females

    This is a randomized comparative effectiveness study of two forms of enhanced prenatal care among 657 Medi-Cal eligible pregnant individuals in Fresno, California. The goal is to see whether group prenatal care with wrap around services versus…

    at UCSF

  • Resources, Inspiration, Support and Empowerment (RISE) for Black Pregnant Women

    open to eligible females ages 18-65

    Perinatal Mood and Anxiety Disorders (PMADs) encompass a range of mental health disorders that occur during pregnancy and up to one year postpartum. Approximately 13% of women experience PMADs. This rate doubles for those with adverse perinatal…

    at UCLA

  • Periviable GOALS Decision Support Tool

    open to eligible people ages 18 years and up

    The Periviable GOALS (Getting Optimal Alignment around Life Support) decision support tool (DST) is meant to facilitate informed shared decision-making regarding neonatal resuscitation for families facing the threat of a periviable delivery…

    at UCSD UCSF

  • Commercial or Open Source Closed Loop Impact on Pregnancy Study

    open to eligible females ages 18 years and up

    The goal of this observational study is to better understand what happens when pregnant people with type 1 diabetes (T1D) use automated insulin delivery (AID) systems. The main questions this study aims to answer are: - What are the maternal and…

    at UCSF

  • Kesimpta (Ofatumumab) Pregnancy Registry

    open to eligible people ages 18-100

    The Kesimpta Pregnancy Registry is an observational, exposure cohort designed study to examine pregnancy and infant outcomes in women and infants who are exposed to Kesimpta (ofatumumab) during pregnancy to treat MS.

    at UCSD

  • Monitoring Pregnancy and Infant Outcomes Following Tralokinumab Exposure During Pregnancy in the US and Canada - PROTECT

    open to eligible females

    The goal of this observational study is to learn about exposure to tralokinumab during pregnancy, as well as atopic dermatitis (AD) during pregnancy. The main question the study aims to answer is whether pregnant people who have been exposed to…

    at UCSD

  • Properties of Antiretroviral and Anti-Tuberculosis Drugs During Pregnancy and Postpartum

    open to eligible females

    The purpose of this study is to evaluate the pharmacokinetic (PK) properties of antiretroviral (ARV) and anti-tuberculosis (TB) drugs administered during pregnancy and postpartum.

    at UCLA UCSD

  • Specimen Collection from Pregnant Women At Increased Risk for Fetal Aneuploidy

    open to eligible females ages 18 years and up

    The specimen collection is designed for the purpose of the development of a noninvasive prenatal test for T21.

    at UCSD

  • Stelara and Tremfya Pregnancy Exposure Registry OTIS Autoimmune Diseases in Pregnancy Project

    open to eligible females

    The purpose of the OTIS Autoimmune Diseases in Pregnancy Study is to monitor planned and unplanned pregnancies exposed to certain medications, to evaluate the possible teratogenic effect of these medications and to follow live born infants for one…

    at UCSD

  • UCLA Perinatal Biospecimen Repository

    open to all eligible people

    The purpose of this investigator-initiated prospective observational cohort study is to establish the new UCLA Perinatal Biospecimen Repository (Perinatal Repository) for collection, storage, and distribution of the human data and biospecimens of…

    at UCLA

  • B Cell Levels In Infants Potentially Exposed To Ocrelizumab During Pregnancy

    Sorry, in progress, not accepting new patients

    This study will evaluate the potential placental transfer of ocrelizumab in women with clinically isolated syndrome (CIS) or multiple sclerosis (MS) [in line with the locally approved indications] whose last dose of ocrelizumab was administered any…

    at UCSF

  • Automated Insulin for Management of Intrapartum Glycemia

    Sorry, not yet accepting patients

    The goal of this clinical trial is learn if automated insulin delivery (AID) systems can be used for glucose management during labor/delivery for pregnant people with type 1 diabetes (T1D). The main questions this study aims to answer are - What are …

    at UCSF

  • CGM for Management of Type 2 Diabetes in Pregnancy

    Sorry, not yet accepting patients

    The goal of this clinical trial is to learn if continuous glucose monitoring works better than self-monitoring of blood glucose (fingersticks) to treat type 2 diabetes in pregnancy. It will also learn about all risk factors (biologic, personal,…

    at UCSD

  • Conscious Pregnancy: Supporting Maternal Cardiometabolic Health with Mindfulness

    Sorry, not yet accepting patients

    A pilot randomized control trial (RCT) to examine the efficacy of a culturally tailored mindfulness intervention upon fasting cardiometabolic factors (including markers of glycemic control) and inflammatory gene expression in n=60 (n=30…

    at UC Irvine

  • CREATE - Cabotegravir & Rilpivirine Antiretroviral Therapy in Pregnancy

    Sorry, not yet accepting patients

    This is a Phase I/II, multicenter, open-label, non-randomized study with four groups to characterize the pharmacokinetics and safety of Cabotegravir (CAB) and Rilpivirine (RPV) long-acting injectable (LA) during pregnancy and postpartum among people …

    at UCSD

  • DECIDE: A Comparative Effectiveness Trial of Metformin Versus Insulin for the Treatment of Gestational Diabetes

    Sorry, not currently recruiting here

    This is a non-inferiority patient-centered and pragmatic comparative-effectiveness pregnancy randomized controlled trial (RCT) with postpartum maternal and child follow-up through 2 years of 1,572 individuals with gestational diabetes mellitus (GDM) …

    at UCSF

  • Developing and Testing the Jenga Dada Intervention in Kenya

    Sorry, not yet accepting patients

    This study aims to work with women's economic empowerment groups within the community to address reproductive coercion and intimate partner violence and promote economic self-sufficiency among women (aged 15+ years). Based on the investigators'…

    at UCSD

  • Tolerability of VeraCept IUD

    Sorry, in progress, not accepting new patients

    To assess the contraceptive efficacy (prevention of pregnancy) of VeraCept

    at UC Davis

  • Tolerability of LevoCept

    Sorry, not yet accepting patients

    To assess the contraceptive efficacy (prevention of pregnancy) of LevoCept

    at UC Davis

  • Goals for Reaching Optimal Wellness: GROWell

    “We're looking for healthy pregnant people to participate in a mobile health program”

    Sorry, in progress, not accepting new patients

    Despite the negative consequences to maternal-child health from women gaining too much weight during pregnancy, up to 62% of overweight and obese women gain more pregnancy weight than is recommended. This project will establish the efficacy of Goals …

    at UC Davis

  • Natural Versus Programmed Frozen Embryo Transfer (NatPro)

    Sorry, in progress, not accepting new patients

    NatPro is a two-arm, parallel-group, multi-center, randomized trial in which women undergoing frozen embryo transfer (FET) will be randomized to receive either a modified natural cycle (corpus luteum present) or a programmed cycle (corpus luteum…

    at UCSF

  • Rigorous Evaluation of Yes and Know, a Fully Virtual Sexual Health and Well-Being Intervention for Youth

    Sorry, not yet accepting patients

    This study is a 2-arm cluster randomized controlled trial with approximately 1,200 youth aged 14-19 years to assess the effectiveness of Yes and Know, a sexual health education program. To be eligible, participants must be 14-19 years old and…

    at UCSF

  • Pregnancy In the CoRonavirus (COVID-19) pandEmic

    Sorry, in progress, not accepting new patients

    Prospective nationwide cohort study of pregnant women enrolled early in gestation and followed for Covid-19 exposure and infection, with follow up of obstetrical outcomes and infant development through the first year of life.

    at UCSF

  • Attitudes and Decision-making After Pregnancy Testing Study

    Sorry, in progress, not accepting new patients

    The ADAPT Study is a longitudinal observational cohort study examining women's pregnancy preferences, pregnancy decision-making processes, and the effects of less preferred (commonly called "unintended") pregnancy on women's lives. This study will…

    at UCSF

  • MIRACLE of LIFE Study

    Sorry, in progress, not accepting new patients

    The goal of this observational study is to develop and validate cell-free RNA-based biomarkers for predicting a variety of adverse pregnancy outcomes in a pregnant person population. The main question it aims to answer are: 1. Can cell-free…

    at UCSD

  • Pregnancy in Women with Cystic Fibrosis

    Sorry, in progress, not accepting new patients

    In this study, the investigators aim to evaluate changes in lung function in women with cystic fibrosis (CF) during pregnancy and for 2 years after pregnancy based on exposure to highly effective cystic fibrosis transmembrane conductance regulator…

    at UCSD

Our lead scientists for Pregnancy research studies include .

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