Primary Immunodeficiency Diseases clinical trials at University of California Health
6 in progress, 4 open to eligible people
Adenovirus-specific Cytotoxic T-lymphocytes for Refractory Adenovirus Infection
open to eligible people ages 1 month to 79 years
Related donor Adenovirus (ADV) specific cytotoxic T cells (CTLs) manufactured with the Miltenyi CliniMACS Prodigy Cytokine Capture System will be administered intravenously in in children, adolescents and young adults with refractory ADV infection post Allogeneic Hematopoietic Stem Cell Transplantation (AlloHSCT), with primary immunodeficiencies (PID) or post solid organ transplant. Funding Source: FDA OOPD
at UCLA UCSF
EBV-specific Cytotoxic T-lymphocytes (CTLs) for Refractory EBV Infection
open to eligible people ages 1 month to 79 years
Related donor Epstein-Barr Virus (EBV) specific cytotoxic T cells (CTLs) manufactured with the Miltenyi CliniMACS Prodigy Cytokine Capture System will be administered in children, adolescents and young adults with refractory EBV infection post Allogeneic Hematopoietic Stem Cell Transplantation (AlloHSCT), with primary immunodeficiencies (PID) or post solid organ transplant. Funding Source: FDA OOPD
at UCLA UCSF
Treatment of Refractory BK Infections With Related Donor BK Specific Cytotoxic T-cells (CTLs)
open to eligible people ages 1 month to 79 years
BK cytotoxic T cells (CTLs) manufactured with the Miltenyi CliniMACS Prodigy Cytokine Capture System will be safe and effective in decreasing specific viral load in children, adolescents and young adults (CAYA) with refractory BK infection post Allogeneic Hematopoietic Stem Cell Transplantation (AlloHSCT) or with primary immunodeficiencies (PID).
at UCSF
Virus Specific Cytotoxic T-Lymphocytes (CTLs) for Refractory Cytomegalovirus (CMV)
open to eligible people ages 1 month to 79 years
CMV cytotoxic T cells (CTLs) manufactured with the Miltenyi CliniMACS Prodigy Cytokine Capture System will be administered in children, adolescents and young adults (CAYA) with refractory cytomegalovirus (CMV) infection post Allogeneic Hematopoietic Stem Cell Transplantation (AlloHSCT), with primary immunodeficiencies (PID) or post solid organ transplant. Funding Source: FDA OOPD
at UCSF
About How TAK-881 is Processed by the Body and Side Effects in People With Primary Immunodeficiency Diseases
Sorry, in progress, not accepting new patients
The main aim of this study is to compare the pharmacokinetics (PK) of subcutaneous (SC) administration of TAK-881 with HYQVIA in participants with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). The participants who are already receiving intravenous immunoglobulin G (IGIV)/conventional subcutaneous intravenous immunoglobulin G (cIGSC) will be treated with HYQVIA or TAK-881 with the same dose and dosing interval of immunoglobulin for up to 24 weeks. Participants will need to visit the clinic every 3 or 4 weeks during the duration of the study.
at UC Irvine
Tabelecleucel in Participants with Epstein-barr Virus-associated Diseases
Sorry, not currently recruiting here
The purpose of this study is to assess the efficacy and safety of tabelecleucel in participants with Epstein-Barr virus (EBV) associated diseases.
at UC Davis UCLA
Our lead scientists for Primary Immunodeficiency Diseases research studies include Christopher Dvorak.
Last updated: