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Spinal Deformity clinical trials at University of California Health

6 in progress, 4 open to eligible people

Showing trials for
  • Complex Adult Deformity Surgery (CADS)

    open to eligible people ages 18 years and up

    Evaluate surgical treatment outcomes and identify best practice guidelines for complex adult spinal deformity (ASD) patients, including radiographic and clinical outcomes, surgical and postoperative complications, risk factors for and revision surgery rates, and the role of standard work to improve patient outcomes and reduce surgical and postoperative complications.

    at UC Davis UCSF

  • Evaluating and Establishing the Relationship in the Five Critical X-ray Time Points in Spinal Deformity Realignment

    open to eligible people ages 18-80

    To establish the relationship in the five critical X-ray time points during multilevel posterior column osteotomies (MPCO) spinal deformity realignment in patients with adult spinal deformity and to follow the participants longitudinally to examine any follow-up X-rays and clinical data to compare to the post-operative standing scan and pre-operative data.

    at UCSD

  • Complex Adult Spinal Deformity (CAD) Treated With Minimally Invasive Surgery

    open to eligible people ages 18 years and up

    Evaluate surgical treatment outcomes and identify best practice guidelines for complex adult spinal deformity (ASD) patients treated with minimally invasive approach, including radiographic and clinical outcomes, surgical and postoperative complications, risk factors for and revision surgery rates, and the role of standard work to improve patient outcomes and reduce surgical and postoperative complications.

    at UCSF

  • Case-Control Analysis of the VersaTie Posterior Fixation System to Prevent Proximal Junctional Failure in Long Posterior Spinal Fusion Constructs for Adult Patients

    open to eligible people ages 18 years and up

    Prospective, Multicenter, Case-Control Analysis of the VersaTie Posterior Fixation System to Prevent Proximal Junctional Failure in Long Posterior Spinal Fusion Constructs for Adult Patients

    at UCSF

  • Tranexamic Acid to Reduce Blood Loss in Spine Trauma Surgery

    Sorry, not currently recruiting here

    This study is designed to evaluate the efficacy of topical tranexamic acid to reduce perioperative blood loss, reduction in postoperative drain output and allogenic transfusion requirements. The proposed study will be a prospective, randomized, double-blind (subject, surgeons, investigators, research coordinators) placebo-controlled study. Patients following high energy trauma who have sustained thoracic or lumbar spine fractures, dislocations or ligamentous injury with resultant instability requiring posterior spinal fusion will be enrolled for this study. Furthermore, patients undergoing elective complex deformity surgery will also be enrolled. Both populations of patients will be randomized into two groups. Group I will receive standard of care operative fixation with topical tranexamic acid intervention (test); Group II will receive standard of care operative fixation with normal saline (placebo) intervention. This study will have a 2-year follow-up and will consist of three periods: screening/enrollment phase up to 21 days from the day of injury to the day of randomization and operative intervention, an inpatient data collection period for 4 days postoperative, and then a follow-up period for 2-years postoperative (visits occurring at 2 week, 16 week, 1 year, and 2 year) time points.

    at UCSF

  • Adult Spinal Deformity Outcomes Database Registry

    Sorry, in progress, not accepting new patients

    The clinical, radiographic, and HRQL outcomes will be compared in operative and nonoperative adult spinal deformity patients.

    at UC Davis UCSF

Our lead scientists for Spinal Deformity research studies include .

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