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Trauma Injury clinical trials at UC Health

2 in progress, 0 open to eligible people

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  • Perineural Local Anesthetic Administration With a Continuous Infusion Versus Automatic Intermittent Boluses

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    This will be a randomized comparison of continuous local anesthetic infusion with patient controlled boluses (PCA) to automated boluses with PCA for continuous popliteal sciatic nerve blocks. The goal will be to determine the relationship between method of local anesthetic administration (continuous with PCA initiated at discharge vs. intermittent dosing with PCA with a 5-hour delay) for continuous peripheral nerve block and the resulting pain control and duration of analgesia.

    at UCSD

  • Traumatic Injury Clinical Trial Evaluating Tranexamic Acid in Children: An Efficacy Study

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    Trauma is the leading cause of death and disability in children in the United States. The objective of this study is to evaluate the benefits and harms of tranexamic acid (TXA; a drug that stops bleeding) in severely injured children with hemorrhagic brain and/or torso injuries. Using thromboelastography, we will measure baseline fibrinolysis to assess for treatment effects of TXA at different levels of fibrinolysis.

    at UC Davis

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