Healthy Volunteers
healthy people welcome
study started
estimated completion
Principal Investigator
by Paul D Blanc, MD MSPH (ucsf)
Photo of Paul D Blanc
Paul D Blanc



The purpose of the study is to better understand the health, including lung health, of Veterans who deployed in support of Operation Enduring Freedom (OEF), Operation Iraqi Freedom (OIF), or Operation New Dawn (OND) and other deployments following these Operations.

Official Title

CSP #595 - Pulmonary Health and Deployment to Southwest Asia and Afghanistan


The aim of the study is to characterize the impact of deployment-related pollution exposures during the Post-9/11 Gulf War Era on current respiratory health using objectively ascertained and standardized physiologic and epidemiologic measures. The primary objective in support of this aim is to assess the association of cumulative exposure to PM2.5 during deployments to the U.S. bases and other locations in Central Asia (Afghanistan and Kyrgyzstan), Southwest Asia (Iraq, Kuwait, Qatar, and United Arab Emirates) and Africa (Djibouti) with current measures of pulmonary function. Secondary objectives in support of the aim will examine the association of cumulative exposure to PM2.5 during deployments with the clinical outcome of medically-treated asthma. The investigators will also explore the impact of deployment duration on both pulmonary function and asthma. This study will execute 4 distinct efforts to meet the study objectives: (1) enroll a study cohort of up to 6,200 Veterans who live within the catchment area of 6 VA recruitment sites, conduct an in-person assessment of pulmonary function, and collect data on key covariates; (2) create a spatial-temporal exposure grid of environmental PM2.5 levels averaged per week per 1 square kilometer at locations where military personnel served; (3) link each individual's location and duration (spatial-temporal) history during deployed and non-deployed times with averaged PM exposures during each of these time periods; and (4) conduct association analyses to test hypotheses of deployment-related cumulative PM2.5 exposure and current respiratory health by combining exposure data with data collected from the cohort members and from their military records.


Pulmonary Function Pulmonary Lung Military and environmental exposures Epidemiologic Observational Interview or questionnaire Deployment related Enduring Freedom Iraqi Freedom Post-9/11 Gulf War Era Veterans


You can join if…

  • Served during the Post-9/11 Gulf War Era in a service branch that had land-based deployments (Air Force, Army, and Marine Corps)
  • Deployed to Afghanistan, Kyrgyzstan, Iraq, Kuwait, Qatar, United Arab Emirates, or Djibouti after October 1, 2001

You CAN'T join if...

  • Active duty at the time of recruitment
  • Impaired decision making capacity
  • No English language proficiency
  • Prisoners


  • VA San Diego Healthcare System, San Diego, CA accepting new patients
    San Diego California 92161 United States
  • VA Puget Sound Health Care System Seattle Division, Seattle, WA accepting new patients
    Seattle Washington 98108 United States

Lead Scientist at University of California Health


accepting new patients
Start Date
Completion Date
VA Office of Research and Development
Study Type
Observational [Patient Registry]
Last Updated