for people ages 18-90 (full criteria)
Healthy Volunteers
healthy people welcome
study started
estimated completion
Principal Investigator
by Philip Weissbrod (ucsd)
Headshot of Philip Weissbrod
Philip Weissbrod



This study seeks to explore whether heart rate variability (HRV) biofeedback can be effective in the treatment of chronic cough. Chronic cough has many causes, including asthma, postnasal drip, and gastroesophageal reflux disease (GERD), each with a specific treatment. However, among a subset of cough patients, no clear cause is found despite extensive workup, and traditional treatment methods do not provide relief. Several studies revealed less common causes of chronic cough and disordered breathing such as vagal neuropathy, paradoxical vocal fold motion, and stress. Additional research identified links between the neurological networks that produce the cough reflex and those that maintain normal breathing. HRV biofeedback is a self-regulation technique that uses computer equipment to monitor heart rate and breathing, two key functions of the autonomic nervous system. By using this non-invasive behavioral technique, cough patients can regulate their breathing and autonomic function, potentially leading to improved autonomic balance and a reduction in cough symptoms.


Cough Voice Therapy Voice Therapy and Heart Rate Variability Biofeedback Heart Rate Variability Biofeedback


You can join if…

Open to people ages 18-90

  • 8+ weeks of cough, Fluent English speaker, Have access to an electronic mobile device

You CAN'T join if...

  • On neuromodulator therapy, cardiac arrhythmia, dysphagia, prior HRVB or mindfulness, head and neck surgery of the oropharynx, neck or larynx, lung surgery, pulmonary pathology other than asthma, tourette syndrome, ACE inhibitor use, current or recent smoker.

Added exclusion criteria as of March 2020 - history of COVID+.


  • UCSD Center for Voice and Swallowing accepting new patients
    San Diego California 92122 United States

Lead Scientist at University of California Health

  • Philip Weissbrod (ucsd)
    Dr. Philip Weissbrod, joined the UC San Diego faculty in 2011 as an assistant professor of surgery in the division of otolaryngology, and serves as the director of the Center for Voice and Swallowing. He is certified by the The American Board of Otolaryngology and is fellowship trained in laryngology, a subspecialty that encompasses voice, swallowing, and upper airway disorders.


accepting new patients
Start Date
Completion Date
University of California, San Diego
Study Type
Expecting 45 study participants
Last Updated