Summary

for people ages 21-45 (full criteria)
healthy people welcome
at UCLA
study started
estimated completion
Holly R Middlekauff (ucla)

Description

Summary

Randomized controlled trial of acute use of electronic cigarette or tobacco cigarette on parameters of ventricular repolarization.

Details

Non-user or chronic electronic cigarette (EC) users will use an EC or control on three occasions:1) EC with nicotine, 2) EC without nicotine, 3) empty EC (control).

Chronic tobacco cigarette (TC) smokers will use a TC or control on three occasions: 1) TC with nicotine (subject's own brand), 2) research TC with very low nicotine, 3) straw (control). The electrocardiogram will be recorded before and after acute exposures and analyzed for parameters representative of ventricular repolarization.

Keywords

Sudden Cardiac Death Prolonged QTc Interval e-cigarettes tobacco cigarettes nicotine ventricular repolarization Death Death, Sudden, Cardiac EC with nicotine EC without nicotine TC with nicotine (own brand) research TC with very low level nicotine Chronic EC user Chronic TC smoker

Eligibility

You can join if…

Open to people ages 21-45

  • Healthy non-smokers chronic TC smokers (non-e-cig users) Chronic EC smokers (Non-TC smokers)

You CAN'T join if...

  • Cardiac disease, respiratory disease, diabetes

Location

  • UCaliforniaLA accepting new patients
    Los Angeles California 90095 United States

Lead Scientist

Details

Status
accepting new patients
Start Date
Completion Date
(estimated)
Sponsor
University of California, Los Angeles
ID
NCT03916341
Study Type
Interventional
Last Updated