for people ages 55 years and up (full criteria)
Healthy Volunteers
healthy people welcome
study started
estimated completion



Study is a randomized clinical trial evaluating the efficacy of novel mobile application technologies (including Seeing AI, Aira, and Supervision+) to improve quality of life in older adults with low vision by expanding community access and providing assistance with activities of daily living. Aira provides real-time remote personal assistance through a sighted Aira agent supplying direct feedback to assist with visual tasks. Seeing AI provides optical character recognition allowing any text to be read aloud, color identification, bar code reading, scene description, and facial recognition based on stored photos. Supervision + allows one to use the phone as a magnifier, providing magnification and contrast enhancement using the camera of the mobile phone. This study seeks to understand the potential of these technologies to improve daily activities, community participation, independence, and self-sufficiency in this group by examining a technological approach, which has not yet undergone rigorous investigation in a diverse population of older adults with visual impairment. Project objectives are to evaluate mobile applications in a wide range of visual disability, categorized into three groups: (1) mild to moderate visual acuity loss, (2) severe to profound visual acuity loss, and (3) legal blindness secondary to visual field loss. Participants are randomized to one of three intervention groups: (1) Supervision+ application, (2) Aira application, or (3) Seeing AI application for a period of 6 months. For the Aira intervention group, participants will be assigned either with 'restricted' access (current open access areas plus 30 minutes/month anywhere), or 'unrestricted' access (700 minutes), for a period of 3 months with a 3 month cross-over period. Participants may elect to continue the study for an additional 3 months during which time they have access to all 3 study mobile applications. Outcome measures include assessment of changes at three, six and nine months post-intervention for: visual ability, health state (including depression), self-efficacy, loneliness, life space, distances travelled from the home, and types of services obtained.


Low Vision, Low Vision Rehabilitation, Seeing AI Smart Phone App, Supervision+ Smart Phone App, Aira Smart Phone App


You can join if…

Open to people ages 55 years and up

  • age 55 years + (no upper limit)
  • reside in CA state (for subjects enrolled at UCLA)
  • reside in New England states of MA, NH, CT or RI (for subjects enrolled at NECO)
  • best-corrected visual acuity 20/40 to 20/800 in the better eye or visual field diameter less than 20 degrees in the better eye
  • English speaking
  • Ability to demonstrate proficiency with the smartphone and mobile app at 4 weeks post initial training
  • no previous use of the Aira app, Seeing AI app or Super Vision+ app on a smartphone (<5 uses in lifetime)

You CAN'T join if...

  • out of the country for >2 weeks during study intervention period if cannot use their own international data plan on their own phone
  • unable to successfully complete the initial on-boarding call for Aira service with an agent as documented by the Aira agent's log (if randomized to Aira)
  • schedules not permitting participation in planned study duration (including planning to move or take extended vacation during study period)
  • inability to understand study procedures or communicate responses in a consistent manner (cognitive impairment as per TICS)
  • substance abuse
  • significant hearing loss (unable to hear communication by phone)
  • significant medical condition likely to limit participation or lifespan
  • participating in another clinical trial that involves treatment that could impact visual function during the study period
  • participant in another clinical trial that involves a treatment or intervention that could impact visual functioning
  • begins use of a new vision-related app during the trial period for the study


  • UCLA Stein Eye Institute accepting new patients
    Los Angeles California 90095 United States
  • New England College of Optometry accepting new patients
    Boston Massachusetts 02115 United States


accepting new patients
Start Date
Completion Date
New England College of Optometry
Study Type
Expecting 240 study participants
Last Updated