Micro-UltraSound In Cancer - Active Surveillance

a study on Prostate Cancer

Summary

Eligibility
for males ages 18 years and up (full criteria)
Location
at UCLA
Dates
study started
completion around
Principal Investigator
by Wayne G. Brisbane, MD (ucla)
Headshot of Wayne G. Brisbane
Wayne G. Brisbane

Description

Summary

This study will compare the two imaging modalities (MRI and micro-ultrasound) during Active Surveillance of prostate cancer (PCa). Progression to clinically significant PCa will be assessed by first taking micro-US targeted samples (while blinded to MRI results), followed by MRI targeted samples, finishing with 12 systematic biopsy cores. The primary goal is to compare microUS to MRI for the detection of ≥GG2 PCa at confirmatory biopsy. This study will also collect blood samples from participants to be used for future biomarker studies.

Official Title

Micro-UltraSound In Cancer - Active Surveillance (MUSIC-AS)

Keywords

Prostate Cancer, Active surveillance, micro-ultrasound, Prostatic Neoplasms, High-resolution micro-ultrasound

Eligibility

You can join if…

Open to males ages 18 years and up

  • Adult men with Gleason Grade Group 1 prostate cancer managed by active surveillance who require a confirmatory prostate biopsy

You CAN'T join if...

  • Men who cannot undergo a prostate MRI
  • Men who cannot undergo a prostate biopsy

Locations

  • University of California Los Angeles, Department of Urology accepting new patients
    Los Angeles California 90095 United States
  • University of British Columbia accepting new patients
    Vancouver Alberta V6T 1Z3 Canada
  • Kipnes Urology Centre - Kaye Edmonton Clinic accepting new patients
    Edmonton Alberta T6G1Z1 Canada
  • CIUSSS du Nord-de-L'Ile-De-Montreal accepting new patients
    Montreal Quebec H3L 1K5 Canada

Lead Scientist at University of California Health

  • Wayne G. Brisbane, MD (ucla)
    Assistant Professor-in-Residence, Urology, Medicine. Authored (or co-authored) 51 research publications

Details

Status
accepting new patients
Start Date
Completion Date
(estimated)
Sponsor
University of Alberta
ID
NCT05558241
Study Type
Interventional
Participants
Expecting 210 study participants
Last Updated