This study is in progress, not accepting new patients

Accurate Point of Care Liver Disease Diagnostics

a study on Nonalcoholic Fatty Liver Disease Liver Disease

Summary

Eligibility
for people ages 18 years and up (full criteria)
Location
at UCSD
Dates
study started
completion around
Principal Investigator
by Claude B Sirlin, MD (ucsd)
Headshot of Claude B Sirlin
Claude B Sirlin

Description

Summary

This research study is being conducted to find out more about techniques to non-invasively evaluate liver disease. The investigators are testing a new technology to evaluate the liver (LiverScope®), and they will compare it to other methods to evaluate the liver, including advanced conventional liver MR and liver FibroScan® ultrasound exams. MR exams and FibroScan® ultrasound exams are common exams used to monitor NAFLD. Conventional MR scanners use magnetic fields and radio waves to make pictures of the liver. LiverScope® is a small, portable MR-based device that uses similar, but simplified technology, and can be used on top of an exam table in an outpatient setting. LiverScope® currently is not approved for clinical use.

In this study the investigators will learn how LiverScope® measurements of the liver compare to MR.

Study participants will be asked to complete a one-time visit which includes:

  • LiverScope exam
  • MR exam
  • FibroScan exam (optional)
  • Blood draw
  • Completion of study questionnaires

Keywords

NAFLD, Nonalcoholic Fatty Liver, Liver Diseases, Fatty Liver, Non-alcoholic Fatty Liver Disease, Liverscope® exam, MR exam, FibroScan® exam (optional), Blood draw, Body measurements

Eligibility

You can join if…

Open to people ages 18 years and up

  • Age:18 years or older
  • Known or clinically suspected NAFLD
  • Weight less than 350 lbs (safety limit of MR scanner table)
  • Able to lie on LiverScope® diagnostic table for about 15 min
  • Able to hold breath repeatedly for about 20 s during MR and LiverScope® exams
  • Willing and able to undergo all study procedures

You CAN'T join if...

  • VA patient only; not a UCSD patient
  • UCSD or Livivos study personnel
  • MR contraindication(s)
  • Potential participant states that she knows that she is pregnant, thinks she may be pregnant or states she is trying to become pregnant*
  • Known chronic liver disease other than NAFLD

Location

  • University of California San Diego
    La Jolla California 92037 United States

Lead Scientist at University of California Health

  • Claude B Sirlin, MD (ucsd)
    Professor, Radiology, Vc-health Sciences-schools. Authored (or co-authored) 461 research publications

Details

Status
in progress, not accepting new patients
Start Date
Completion Date
(estimated)
Sponsor
University of California, San Diego
ID
NCT05986916
Study Type
Observational
Participants
Expecting 50 study participants
Last Updated