Not currently recruiting at University of California Health

A Study to Evaluate Alnuctamab in Combination With Mezigdomide in Participants With Relapsed and/or Refractory Multiple Myeloma

a study on Multiple Myeloma

Summary

Eligibility
for people ages 18 years and up (full criteria)
Location
at UCSF
Dates
study started
completion around

Description

Summary

The purpose of this study is to determine the recommended dose and schedule, and evaluate the safety and preliminary efficacy of alnuctamab in combination with mezigdomide in participants with relapsed and/or refractory multiple myeloma.

Official Title

A Phase 1b/2a, Multicenter, Open-label Study to Determine the Recommended Dose and Schedule, and Evaluate the Safety and Preliminary Efficacy of Alnuctamab in Combination With Mezigdomide in Participants With Relapsed and/or Refractory Multiple Myeloma

Keywords

Multiple Myeloma, Plasma Cell Neoplasms, Dexamethasone, Alnuctamab, Mezigdomide

Eligibility

You can join if…

Open to people ages 18 years and up

Participant has a history of RRMM, and must:

  • Part A: Have previously received ≥ 3 prior lines of anti-myeloma therapy.
  • Part B and Part C: Have received 1 to 3 prior lines of anti-myeloma therapy.

You CAN'T join if...

• Must not have previously received alnuctamab or mezigdomide.

Note: Other protocol-defined inclusion/exclusion criteria apply

Locations

  • Local Institution - 0032 not yet accepting patients
    San Francisco California 94143 United States
  • University of Alabama at Birmingham accepting new patients
    Birmingham Alabama 35294 United States
  • Weill Cornell Medical College accepting new patients
    New York New York 10065 United States

Details

Status
accepting new patients at some sites,
but this study is not currently recruiting here
Start Date
Completion Date
(estimated)
Sponsor
Celgene
Links
BMS Clinical Trial Information
ID
NCT06163898
Phase
Phase 1/2 Multiple Myeloma Research Study
Study Type
Interventional
Participants
Expecting 156 study participants
Last Updated