A Randomized Comparison of Personalized Therapy Mgmt Based On Coronary Atherosclerotic Plaque Vs. Usual Care for Symptomatic Patients With Suspicion of CAD

Open to people ages 18 years and up

• > 18 years
• Symptomatic patients with suspicion of CAD, including those referred for elective, non-urgent diagnostic testing (e.g. stress test)

• LDL < 100 mg/dL
• Currently or previously treated beyond primary prevention guidelines
• Suspected acute coronary syndrome or otherwise unstable clinical status
• Planned cardiovascular procedure (e.g. coronary angiography, cardiac surgery, non-coronary vascular procedure)
• Noninvasive or invasive CV testing for CAD within 1 year (e.g. invasive coronary angiography (ICA), coronary CT angiography (CCTA) including calcium scoring)
• Known history of obstructive CAD (prior myocardial infarction, CABG or PCI, stenosis ≥50%)
• Known EF ≤40% or other moderate to severe valvular or congenital cardiac disease
• Contraindications to CCTA