NE3107 in Adults With Neurological Symptoms of Long COVID

Open to people ages 18-69

• 18 years to 69 years of age
• Long COVID with neurological symptoms as defined below:
  1. Current symptoms of at least fatigue and neurocognitive impairment that began or worsened after an index SARS-CoV-2 infection that occurred at least 3 months prior to screening. Index SARS-CoV-2 infection is defined as either: 1) an episode of COVID-19 with a positive nucleic acid or antigen test during acute illness, as documented in the medical record, or 2) a documented clinical diagnosis of COVID-19, which can be based on a patient-reported positive test for COVID-19. Note that a documented diagnosis of Long COVID is not required for inclusion.
  2. Symptoms cannot be explained by any concomitant condition or diagnosis, in the opinion of the investigator.
  3. Symptom duration for at least 3 months. diagnosed with Long COVID with symptoms of fatigue and brain fog for at least 3 months
• Agree to maintain any other regular medications at current doses for the duration of the trial (except for essential need of new medication or dose change, as prescribed by a physician)
• Agree to use birth control measures
• Provide voluntary consent
• Willing to allow blood collection
• Pass all screening tests and procedures

• Has received a COVID-19 vaccination within 14 days
• Previous admission to the intensive care unit for COVID-19
• Medical history of major mental or physical illness prior to COVID-19 infection