This study is not yet accepting patients

Safety and Tolerability Study of Human Neural Stem Cells for Huntington's Disease

a study on Huntington's Disease

Summary

Eligibility
for people ages 18-65 (full criteria)
Location
at UC Irvine
Dates
study started
study ends around

Description

Summary

The purpose of this research study is to determine whether an implantation of hNSC-01 is a safe and tolerable study intervention for Huntington's disease. This study is the first time that hNSC-01 is being tested in people.

Official Title

Phase 1B/2A Study of the Safety and Tolerability of Human Neural Stem Cells for Huntington's Disease

Keywords

Huntington Disease, Huntington's disease, stem cell, REGEN4HD, hNSC-01

Eligibility

For people ages 18-65

Please note this may not be a complete list of eligibility criteria.

Inclusion Criteria:

  • Have decision-making capacity and be able to provide written informed consent.
  • Are between 18 to 65 years of age
  • Have genetically confirmed diagnosis of Huntington's Disease
  • Able to undergo MRI scans, tolerate neurosurgical procedure, blood draws and lumbar puncture.

Exclusion Criteria:

Location

  • University of California, Irvine
    Irvine California 92697 United States

Details

Status
not yet accepting patients
Start Date
Completion Date
(estimated)
Sponsor
Leslie Thompson
ID
NCT07451613
Phase
Phase 1/2 Huntington's Disease Research Study
Study Type
Interventional
Participants
Expecting 21 study participants
Last Updated