Prospective Registry of Histotripsy for Soft Tissue Tumors

Histotripsy is a treatment that uses focused ultrasound waves to break down tissue without surgery. The ultrasound waves meet at a specific spot and turn the tissue into liquid. This study is a prospective observational registry of participants receiving histotripsy. The goal of this study is to gather information about the use of histotripsy to confirm it is safe and effective medical procedure.

PRIMARY OBJECTIVES:

1. Tumor response on imaging will be assessed using standardized criteria for tumor types such as European Association for the Study of the Liver (EASL), Response Evaluation Criteria in Solid Tumors (RECIST), and modified RECIST (mRECIST).
2. Progression free survival and overall survival.
3. Risk factors for adverse events identified by NCI Common Terminology Criteria for Adverse Events (CTCAE).

OUTLINE:

Researchers will collect data from participants' regular doctor visits via medical records for three years after the Histotripsy procedure has taken place.