Novel Body Composition Measurements in Association With Outcomes of Breast Reconstruction Reconstruction

Description

Investigation Into the Utility of Novel Body Composition Measurements in Association With Outcomes of Breast Reconstruction

PRIMARY OBJECTIVES:

SECONDARY OBJECTIVES:

Define the differences in body composition between participants undergoing breast reconstruction who develop complications and those who do not.
To determine the implications of different measures of body composition on outcomes of breast reconstruction.
Compare utility of body composition measurements versus other anthropometric assessments on assessing risk of complications following breast surgery.

OUTLINE: This is a observational study. Participants are assigned to 1 of 2 cohorts and will be follow-up for up to 2 years.

Breast Carcinoma, Breast Cancer, Postmastectomy breast reconstruction, Breast Neoplasms, Measurement of Body Composition, Chart Review, Implant-based Reconstruction, Autologous Reconstruction

Open to people ages 18 years and up

Patients must have histologically confirmed breast malignancy or increased risk of developing a breast malignancy.
Age ≥ 18 years.
Scheduled to undergo mastectomy with immediate breast reconstruction using a permanent implant, tissue expander, or autologous tissue (e.g. Deep Inferior Epigastric Perforator (DIEP) flap, muscle-sparing Transverse Rectus Abdominis Myocutaneous (msTRAM) flap, Profunda Artery Perforator (PAP) flap).
Ability to understand a written informed consent document, and the willingness to sign it.

Any significant medical condition or laboratory abnormalities, which places the subject at unacceptable risk if he/she were to participate in the study.
Pregnant or breastfeeding.
Patients assigned male at birth.
Non-cisgender women.
Patients with implanted electronic medical devices (e.g. pacemaker, defibrillator).
Patients with prosthetic limbs.

University of California accepting new patients
San Francisco California 94143 United States