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Vulvodynia clinical trials at UC Health
2 in progress, 1 open to eligible people

  • Vestibulodynia: Understanding Pathophysiology and Determining Appropriate Treatments

    open to eligible females ages 18-50

    Vestibulodynia (VBD) is a complex chronic vulvar pain condition that impairs the psychological, physical, and sexual health of 1 in 6 reproductive aged women in the United States. Here, the investigators plan to conduct a randomized, double-blinded, placebo-controlled clinical trial to 1) compare the efficacy of peripheral (lidocaine/estradiol cream), centrally-targeted (nortriptyline), and combined treatments in alleviating pain and improving patient-reported outcomes and 2) determine cytokine and microRNA biomarkers that predict treatment response in women with distinct VBD subtypes. Positive findings from this study will readily translate to improved patient care, permitting the millions of women with VBD, their partners, and their clinicians to make more informed decisions about pain management.

    at UCLA

  • Profiling Vulvodynia Based on Neurobiological and Behavioral Endophenotypes

    Sorry, in progress, not accepting new patients

    The investigators plan to extensively phenotype a large sample of Vulvodynia (VD) patients using functional and structural brain imaging together with genetic, physiological, and biological parameters.

    at UCLA

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