Wound Heal clinical trials at University of California Health
4 in progress, 3 open to eligible people
Influence of Sun Protection and Linear Repair of Cutaneous Surgical Defects
open to eligible people ages 18 years and up
The purpose of this study is to determine the potential influence of sun protection on the aesthetic outcome of post-surgical scars following the reconstruction of Mohs micrographic surgery defects via linear repair. This study will be performed as a randomized split-wound study. Half of the wound will be treated with zinc containing sunscreen and the other half of the wound would not be treated. Three-months post-surgery, the scar will be evaluated via the patient observer scar assessment scale (POSAS), a validated scar instrument, as well as a colorimeter to measure the amount of vascularity, and hyperpigmentation between the treated and the non-treated area compared to the 'surrounding skin' defined as skin in the proximity but not adjacent to the wound. Any adverse events will also be recorded.
at UC Davis
Micro/Nanobubbles (MNBs) for Treatment of Acute and Chronic Wounds
open to eligible people ages 18 years and up
The purpose of this study is to assess the safety and efficacy of Micro/nanobubbles (MNB's) for the healing of acute and chronic wounds.
at UC Irvine
Burn Pivotal Study
open to all eligible people
The purpose of this study is to validate the algorithm for burn healing assessment by the Spectral MD DeepView device which would provide burn healing potential assessment.
at UC Davis UCSD
Aesthetic Outcome of Complex Linear Closure vs Second Intention Healing: Below the Knee
Sorry, accepting new patients by invitation only
The purpose of this study is to determine whether complex linear closure vs second intention healing for cutaneous wounds below the knee affects esthetic outcomes (primary outcome). As secondary outcome, the study team plans to look at patient quality of life measures and complications. This will be a prospective, 2-arm, randomized, evaluator-blinded clinical trial. One half of the patients will receive repair by complex linear closure and the other half of the patients will undergo second intention healing. Three-months post-surgery, the scar will be evaluated via the patient observer scar assessment scale (POSAS), a validated scar instrument, as well as the trace-to-tape method, an objective outcome measure for linear postoperative scars. In addition, patients will be provided a validated quality of life survey to complete. Any adverse events will also be recorded.
at UC Davis
Our lead scientists for Wound Heal research studies include Raj Vyas, MD Jeanne Lee, MD Daniel Eisen, MD Kathleen Romanowski, MD.
Last updated: